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Phospholipase D inhibitor enhances radiosensitivity of breast cancer cells

Son JC, Kang DW, Yang KM, Choi KY, Son TG, Min DS

  • KMID: 2154257
  • Exp Mol Med.
  • 2013 Aug;45(8):e38.
Radiation and drug resistance remain the major challenges and causes of mortality in the treatment of locally advanced, recurrent and metastatic breast cancer. Dysregulation of phospholipase D (PLD) has been...
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Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

Cho JW, Park K, Kweon GR, Jang BC, Baek WK, Suh MH, Kim CW, Lee KS, Suh SI

  • KMID: 1056230
  • Exp Mol Med.
  • 2005 Jun;37(3):186-192.
Ultraviolet B (UVB) irradiation of skin induces an acute inflammation. Cyclooxygenase-2 (COX-2) protein plays key roles in acute inflammation in UVB-irradiated keratinocyte cell line HaCaT. Recently, curcumin has been regarded...
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