- Dynorphin and enkephalin mRNAs in the rat forebrain by in situ hynridization histochmistry
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Lee MH, Suh YS
- KMID: 1686711
- Korean J Anat.
- 1992 Jun;25(2):179-187.
No abstract available. -
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- Effects of an Opiate Receptor Antagonist Naloxone on Endotoxic Shock and Tumorigenesis
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Ha TY, Ko YS, Moon SR
- KMID: 1547846
- Korean J Immunol.
- 1997 Mar;19(1):91-106.
Septic shock is one of the leading cause of death in hospitalized patients and mortality rates of up to 50 % have been reported. Despite all efforts, no regimen today... -
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- Immunohistochemical observations on the changes of autoimmune innervation of the human vas deferens after vasectomy
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Park IS, Park YK
- KMID: 2060307
- Korean J Urol.
- 1991 Oct;32(5):774-780.
Immunohistochemical study have been made to examine the autonomic innervation of the human vas dererens following vasectomy one to 7 years previously. Samples from sites on the proximal (testicular) and... -
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- The effects of kainate-induced Seizure on the Opioid Peptide Gene Expression in Rat Hippocampus
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Park KW, Park MK, Kim BJ, Ko SB, Kang YH, Lee DH
- KMID: 1957293
- J Korean Neurol Assoc.
- 1994 Dec;12(4):614-622.
In the rat hippocampal formation, the time-course and dose-response of the expression of enkephalin and dynorphin gene were examined after kainate (KA) treatment with in situ hybridization histochemistry. The KA... -
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- Changes of Neuropeptides in the Basal Ganglia of Hemiparkinsonian Rat Model
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Park KW, Lee DH, Park MK, Kim BJ, Ko SB, Suh YS
- KMID: 1957292
- J Korean Neurol Assoc.
- 1994 Dec;12(4):604-613.
We used in situ hybridization histochemistry with synthetic oligonucleotide probes to examined the effects of unilateral 6-hydroxydopamine lesions (which eliminated tyrosine hydroxylase mRNA containing cells in mesencephalon) on enkephalin, dynorphin,... -
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- Distribution of Neuropeptide mRNA-Containing Neurons and Changes of Their Gene Expression in the Rat Periaqueductal Gray in a Neuropathic Pain Model
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Huh SM, Kim JG, Bae MA, Kim DS, Park MJ, Jo HJ
- KMID: 1529457
- Korean J Anat.
- 1997 Jun;30(3):205-214.
The distribution of enkephalin, dynorphin, substance P and neurotensin in the periaqueductal gray[PAG] has been well established by immunohistochemical methods. However, there is little information about the regional distribution of... -
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- Inhibitory Mechanism of Periaqueductal Gray Matter on Neuropathic Pain in Rat
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Kim BO, Ryu JW, Seo JS, Sohn JH
- KMID: 2174649
- J Korean Acad Rehabil Med.
- 2001 Feb;25(1):110-116.
OBJECTIVE: Using Lee et al (1996) model, we assessed the effect of opioid within the PAG on the manifestations of the neuropathic pain, and we studied the effects of naloxone... -
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- Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes
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Nam MH, Han KS, Lee J, Bae JY, An H, Park S, Oh SJ, Kim E, Hwang E, Bae YC, Lee CJ
- KMID: 2410473
- Exp Neurobiol.
- 2018 Apr;27(2):120-128.
- doi: 10.5607/en.2018.27.2.120
µ-opioid receptor (MOR) is a class of opioid receptors with a high affinity for enkephalins and beta-endorphin. In hippocampus, activation of MOR is known to enhance the neuronal excitability of... -
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- Genomic Changes in the Striatum of Unilateral 6-hydroxydopamine Lesioned Parkinson Rat Model
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Kim BJ, Park KW, Kim H, Lee DH
- KMID: 2342993
- J Korean Neurol Assoc.
- 2002 Jul;20(4):385-393.
BACKGROUND: Parkinson's disease is the primary degenerative disease characterized by rigidity, bradykinesia and resting tremor. Even though dopaminergic cell loss of the substantia nigra compacta is a main pathogenesis of... -
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- The Effects of Dopamin D-1 Agonist (SKF-38393) on Expression of Substance-P & Enkephalin mRNA in the Striatum of Hemiparkinsonian Rat Model
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Lee SH, Kwon DY, Yu SW, Koh SB, Park MK, Kim H, Park KW, Lee DH
- KMID: 2343065
- J Korean Neurol Assoc.
- 2003 Oct;21(5):527-533.
BACKGROUND: The selective D1 dopamine agonist has been known to play a stimulatory role in substance-P synthesis in the striatum, but its effect on the enkephalin mRNA expression has not... -
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- The Gene Expression of Dynorphin, Enkephalin, c-Fos in the Neuropathic Rat
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Han NH, Lee WH, Hwang WJ, Yoon SH, Shin YS, Son SC, Kim HJ, Choi SJ, Lim K, Hwang BD
- KMID: 2239060
- Korean J Anesthesiol.
- 1996 Sep;31(3):293-303.
- doi: 10.4097/kjae.1996.31.3.293
BACKGROUND: We studied the time course of gene expression of dynorphin, enkephalin, c-fos, and the changes of allodynia, and the effect of chemical sympathectomy on the gene expression and allodynia... -
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- The Effect of Unilateral Dopaminergic Deafferentation on Kainic acid Induced Seizures in the Rat
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Park KW, Lee DH
- KMID: 2066049
- J Korean Neurol Assoc.
- 1996 Mar;14(1):114-125.
There has been quite a number of research regarding the role of dopamine in epilepsy and it has been still very controversial, In this study, the effect of dopaminergic deafferentation... -
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- The Effects of Pre-emptive Administration of Ketamine and norBNI on Pain Behavior, c-Fos, and Prodynorphin Protein Expression in the Rat Spinal Cord after Formalin-induced Pain Is Modulated by the DREAM Protein
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Long I, Suppian R, Ismail Z
- KMID: 2074026
- Korean J Pain.
- 2013 Jul;26(3):255-264.
- doi: 10.3344/kjp.2013.26.3.255
BACKGROUND: We investigated the effects of pre-emptive administration of ketamine and norBNI on pain behavior and the expression of DREAM, c-Fos, and prodynorphin proteins on the ipsilateral side of the... -
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- Role of Protein kinase C in Desensitization of Somatostatin-induced Calcium Signalling in NG108-15 Cells
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Kim KM, Sung JH, Kim MJ, Rhie DJ, Jo YH, Hahn SJ, Kim MS, Yoon SH, Kim BS
- KMID: 2100466
- J Korean Soc Endocrinol.
- 2005 Aug;20(4):353-361.
- doi: 10.3803/jkes.2005.20.4.353
BACKGROUND: Activation of G-protein coupled-somatostatin receptors induces the release of calcium from inositol 1, 4, 5-trisphosphate-sensitive intracelluar stores. G-protein-coupled receptor signaling decreases with prolonged exposure to an agonist. SEBJECTS and... -
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- The Effects of Repeated Stress on the Opioidergic Neurotransmission in Rats
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Sakong JK, Lee KH, Koo BH, Kim JS, Lee JB, Ha JH
- KMID: 2340324
- J Korean Neuropsychiatr Assoc.
- 1999 May;38(3):638-646.
OBJECTIVES: Research into emotional or behavioral stress typically focuses upon the hypothalamic-pituitary-adrenal axis. It is well established that the hypothalamic-pituitary-adrenocortical axis is subject to inhibitory control by opioids in... -
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- Pain-reducing Effect by Transplants of Isolated Xenogeneic Chromaffin Cells in Mouse
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Han YM, Lee JP, Hwang HS, Song JH, Park SK, Park SJ, Jin JK, Choi EK, Kim YS, Ahn MS
- KMID: 1955971
- J Korean Neurosurg Soc.
- 2001 Apr;30(4):417-424.
OBJECTIVE: Adrenal medullary chromaffin cells are known to release analgesic substances such as opioides and catecholamines. Transplantation of them is a novel method that challenges current approaches in treating... -
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- The Neuroprotective Effect of delta-opioid Receptor Stimulation with [D-Ala2, D-Leu5] Enkephalin Against Ischemic Neuronal Injury
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Kim H, Lee SW, Park JS, Min JH, Min MK
- KMID: 2333069
- J Korean Soc Emerg Med.
- 2012 Feb;23(1):111-119.
PURPOSE: Oxygen is indispensable for survival and aerobic metabolism in all mammalian cells. Inadequate oxygen triggers a multifaceted cellular response negatively impacting important physiological functions which are observed in clinical... -
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- Nerve Regeneration and Detrusor Contractility after Muscle Precursor Cells Implantation in Unilateral Pelvic Nerve Transected Rat
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Im CM, Kwon DD, Ryu SB
- KMID: 2294037
- Korean J Urol.
- 2005 Aug;46(8):861-866.
Purpose: Preliminary data suggest that muscle precursor cells (MPCs) play a role in the repair of injured tissues by responding to the release of unknown growth factors, which subsequently induce... -
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- Receptor Activation is Not the Main Rescue Mechanism of Morphine in Peroxynitrite-Induced Death of Human Neuroblastoma SH-SY5Y Cells
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Son Y, Ahn JY, Choi YS, Song YK, Yoon JS, Kim TY, Cheong YP
- KMID: 2031566
- Korean J Anesthesiol.
- 2000 Aug;39(2):226-231.
- doi: 10.4097/kjae.2000.39.2.226
BACKGROUND: In the present study, we examined the effect of morphine on NO- and peroxynitrite-induced cell death using a human neuroblastoma SH-SY5Y cell line which abundantly expresses micro, delta and... -
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- The Effect of D-phenylalanine on the Analgesia Produced by Peripheral Nerve Conditioning Stimulation in the Cat
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Kim SH, Nam TS, Lee YH, Kim YH, Paik KS
- KMID: 2016098
- J Korean Neurol Assoc.
- 1991 Jun;9(2):171-185.
An effect of D-phenylalanine on the pain inhibitory mechanism of prolonged electrical stimulation of the peripheral nerve was studied in decerebrate cats and spinal cats. The response of spinal neurons... -
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