- Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Abeta pathology and improves cognitive function
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Kim TK, Han HE, Kim H, Lee JE, Choi D, Park WJ, Han PL
- KMID: 1402318
- Exp Mol Med.
- 2012 Dec;44(12):740-748.
The plant viral protease, NIa, has a strict substrate specificity for the consensus sequence of Val-Xaa-His-Gln, with a scissoring property after Gln. We recently reported that NIa efficiently cleaved the... -
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- Pharmacogenetic Influence of LOC387715/HTRA1 on the Efficacy of Bevacizumab Treatment for Age-Related Macular Degeneration in a Korean Population
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Kang HK, Yoon MH, Lee DH, Chin HS
- KMID: 1499678
- Korean J Ophthalmol.
- 2012 Dec;26(6):414-422.
- doi: 10.3341/kjo.2012.26.6.414
PURPOSE: The purpose of this study was to determine the pharmacogenetic effects of complement factor H (CFH) Y402H, LOC387715 and high-temperature requirement factor A1 (HTRA1) genotypes on the treatment of... -
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