- Down-regulation of human FEN-1 gene expression during differentiation of promyelocytic leukemia cells
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Kim IS
- KMID: 755017
- Exp Mol Med.
- 1998 Dec;30(4):252-256.
Flap endo/exonuclease-1 (FEN-1) recognizes 5'-flap DNA structures that have been proposed to be important intermediates in DNA replication, repair and recombination, and cleaves the double strand-single strand junction of flap ... -
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- Human FEN-1 can process the 5'-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner
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Lee SM, Park MS
- KMID: 931883
- Exp Mol Med.
- 2002 Sep;34(4):313-317.
Trinucleotide repeat (TNR) instability can cause a variety of human genetic diseases including myotonic dystrophy and Huntington's disease. Recent genetic data show that instability of the CAG/CTG repeat DNA... -
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