- Elevated Circulating Sclerostin Levels in Frail Older Adults: Implications beyond Bone Health
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Baek JY, Ahn SH, Jang IY, Jung HW, Ji E, Park SJ, Jo Y, Lee E, Ryu D, Hong S, Kim BJ
- KMID: 2565255
- Endocrinol Metab.
- 2025 Feb;40(1):73-81.
- doi: 10.3803/EnM.2024.2100
Background: Sclerostin, initially recognized for its pivotal role in bone metabolism, has gained attention for its multifaceted impact on overall human health. However, its influence on frailty—a condition that best... -
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- Carnitine Metabolite as a Potential Circulating Biomarker for Sarcopenia in Men
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Seo JH, Koh JM, Cho HJ, Kim H, Lee Y, Kim SJ, Yoon PW, Kim W, Bae SJ, Kim HK, Yoo HJ, Lee SH
- KMID: 2565257
- Endocrinol Metab.
- 2025 Feb;40(1):93-102.
- doi: 10.3803/EnM.2024.2117
Background: Sarcopenia, a multifactorial disorder involving metabolic disturbance, suggests potential for metabolite biomarkers. Carnitine (CN), essential for skeletal muscle energy metabolism, may be a candidate biomarker. We investigated whether CN... -
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- Treatment of Graves’ Disease: Faster Remission or Longer but Safe, That Is the Question
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Jung CH
- KMID: 2565254
- Endocrinol Metab.
- 2025 Feb;40(1):70-72.
- doi: 10.3803/EnM.2025.2333
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- Highlights of the Most Recent American Diabetes Association Guidelines: From Evidence to Practice
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Kim MK
- KMID: 2565253
- Endocrinol Metab.
- 2025 Feb;40(1):67-69.
- doi: 10.3803/EnM.2025.2329
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- Redefining Polycystic Ovary Syndrome: Transformative Diagnostic and Management Changes in the 2023 Guidelines
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Hong AR
- KMID: 2565252
- Endocrinol Metab.
- 2025 Feb;40(1):64-66.
- doi: 10.3803/EnM.2024.2263
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- Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data
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Hong S, Han K, Park CY
- KMID: 2565246
- Endocrinol Metab.
- 2025 Feb;40(1):1-9.
- doi: 10.3803/EnM.2024.2285
Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap,... -
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- Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications
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Lee J, Lee NK, Moon JH
- KMID: 2565247
- Endocrinol Metab.
- 2025 Feb;40(1):10-25.
- doi: 10.3803/EnM.2024.2264
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth,... -
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- Tirzepatide and Cancer Risk in Individuals with and without Diabetes: A Systematic Review and Meta-Analysis
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Kamrul-Hasan A, Alam MS, Dutta D, Sasikanth T, Aalpona FTZ, Nagendra L
- KMID: 2565259
- Endocrinol Metab.
- 2025 Feb;40(1):112-124.
- doi: 10.3803/EnM.2024.2164
Background: Data on the carcinogenic potential of tirzepatide from randomized controlled trials (RCTs) are limited. Furthermore, no meta-analysis has included all relevant RCTs to assess the cancer risk associated with... -
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- Evolving Characteristics of Type 2 Diabetes Mellitus in East Asia
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Lee J, Yoon KH
- KMID: 2565251
- Endocrinol Metab.
- 2025 Feb;40(1):57-63.
- doi: 10.3803/EnM.2024.2193
In East Asians, type 2 diabetes mellitus (T2DM) is primarily characterized by significant defects in insulin secretion and comparatively low insulin resistance. Recently, the prevalence of T2DM has rapidly increased... -
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- Unveiling Risk Factors for Treatment Failure in Patients with Graves’ Disease: A Nationwide Cohort Study in Korea
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Kim JA, Kim KJ, Choi J, Kim KJ, Song E, Yu JH, Kim NH, Yoo HJ, Seo JA, Kim NH, Choi KM, Baik SH, Kim SG
- KMID: 2565260
- Endocrinol Metab.
- 2025 Feb;40(1):125-134.
- doi: 10.3803/EnM.2024.2093
Background: Antithyroid drug (ATD) treatment is the preferred initial treatment for Graves’ disease (GD) in South Korea, despite higher treatment failure rates than radioactive iodine (RAI) therapy or thyroidectomy. This... -
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- Long-Term Efficacy and Safety of Denosumab: Insights beyond 10 Years of Use
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Ha J, Lee YJ, Kim J, Jeong C, Lim Y, Lee J, Baek KH, on Behalf of the Catholic Medical Center Bone Research Group
- KMID: 2565250
- Endocrinol Metab.
- 2025 Feb;40(1):47-56.
- doi: 10.3803/EnM.2024.2125
Osteoporosis management in post-menopausal women focuses on fracture prevention, with denosumab as a key therapeutic option. Despite its proven efficacy in reducing fracture risk and increasing bone mineral density (BMD)... -
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- Medical Treatment of Cushing’s Syndrome
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Guignat L, Bertherat J
- KMID: 2565248
- Endocrinol Metab.
- 2025 Feb;40(1):26-38.
- doi: 10.3803/EnM.2024.501
Endogenous Cushing’s syndrome (CS) refers to the manifestations of chronic cortisol excess. This rare disease is associated with multiple comorbidities, impaired quality of life, and increased mortality. The management of... -
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- Development of a Long-Acting Follicle-Stimulating Hormone Using Serum Albumin Fab-Associated Technology for Female Infertility
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Kim D, Cho YH, Kang MJ, Lee SJ, Lee S, Yun BH, Chi H, An J, Lee K, Han J, Chi S, Song MY, Cha SH, Lee EJ
- KMID: 2565262
- Endocrinol Metab.
- 2025 Feb;40(1):146-155.
- doi: 10.3803/EnM.2024.2090
Background: Recombinant human follicle-stimulating hormone (rhFSH) is commonly used to treat female infertility, but its short half-life necessitates multiple doses. Even corifollitropin alfa, with an extended half-life, requires supplementary injections... -
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- Triiodothyronine Is Associated with Incidence/Resolution of Steatotic Liver Disease: Longitudinal Study in Euthyroid Korean
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Kim HI, Kim JY, Cho JH, Han JM, Suh S, Bae JC, Kim TH, Kim SW, Hahm JR, Chung JH
- KMID: 2565261
- Endocrinol Metab.
- 2025 Feb;40(1):135-145.
- doi: 10.3803/EnM.2024.2040
Background: The positive relationship between triiodothyronine (T3) and steatotic liver disease (SLD) demonstrated only in crosssectional study. We aimed to evaluated whether total T3 (TT3) is associated with the development/resolution... -
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- Metabolic Consequences of Glucagon-Like Peptide-1 Receptor Agonist Shortage: Deterioration of Glycemic Control in Type 2 Diabetes
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Choe HJ, Nauck MA, Moon JH
- KMID: 2565263
- Endocrinol Metab.
- 2025 Feb;40(1):156-160.
- doi: 10.3803/EnM.2024.2150
In the context of a global shortage of glucagon-like peptide-1 (GLP-1) receptor agonists, we assessed the impact of discontinuing dulaglutide on metabolic control in individuals with type 2 diabetes. Our... -
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- Risk of Diabetes Mellitus in Adults with Intellectual Disabilities: A Nationwide Cohort Study
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Koo HY, Cho IY, Um YJ, Park YMM, Kim KM, Lee CE, Han K
- KMID: 2565258
- Endocrinol Metab.
- 2025 Feb;40(1):103-111.
- doi: 10.3803/EnM.2024.2126
Background: Intellectual disability (ID) may be associated with an increased risk of diabetes mellitus (DM). However, evidence from longitudinal studies is scarce, particularly in Asian populations. Methods: This retrospective cohort study... -
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- Elevated Fracture Risks in Patients Using Inhaled Corticosteroids: A Korean Nationwide Study
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Kong SH, Jo AJ, Park CM, Park KI, Yun JE, Kim JH
- KMID: 2565256
- Endocrinol Metab.
- 2025 Feb;40(1):82-92.
- doi: 10.3803/EnM.2024.1990
Background: In this comprehensive retrospective nationwide cohort study, we examined the relationships between various asthma medications and bone health, utilizing data from the National Health Insurance Service database of South... -
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- Pituitary Neuroendocrine Tumors in Multiple Endocrine Neoplasia
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Chin SO, Chik C, Tateno T
- KMID: 2565249
- Endocrinol Metab.
- 2025 Feb;40(1):39-46.
- doi: 10.3803/EnM.2024.2074
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant disorder characterized by tumors of the pituitary, parathyroid, and endocrine-gastrointestinal tract. Pituitary neuroendocrine tumors (PitNETs) occur in about 40% of MEN1... -
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