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Response: Favorable Glycemic Control with Once-Daily Insulin Degludec/Insulin Aspart after Changing from Basal Insulin in Adults with Type 2 Diabetes (Endocrinol Metab 2019; 34:382-9, Han Na Jang et al.)

Jang HN, Jung HS

  • Endocrinol Metab.
  • 2020 Mar;35(1):194-195.
  • doi: 10.3803/EnM.2020.35.1.194
No abstract available.
Letter: Favorable Glycemic Control with Once-Daily Insulin Degludec/Insulin Aspart after Changing from Basal Insulin in Adults with Type 2 Diabetes (Endocrinol Metab 2019; 34:382-9, Han Na Jang et al.)

Rhee SY

  • Endocrinol Metab.
  • 2020 Mar;35(1):192-193.
  • doi: 10.3803/EnM.2020.35.1.192
No abstract available.
Novel ABCD1 Gene Mutation in a Korean Patient with X-Linked Adrenoleukodystrophy Presenting with Addison's Disease

Cho YK, Lee SY, Kim SW

  • Endocrinol Metab.
  • 2020 Mar;35(1):188-191.
  • doi: 10.3803/EnM.2020.35.1.188
X-linked adrenoleukodystrophy (X-ALD) occurs due to mutations in the ABCD1 gene that encodes the peroxisomal membrane protein peroxisomal transporter ATP-binding cassette sub-family D member 1 (ABCD1). Degradation of very long-chain...
Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas

Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ

  • Endocrinol Metab.
  • 2020 Mar;35(1):177-187.
  • doi: 10.3803/EnM.2020.35.1.177
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing...
Visceral-to-Subcutaneous Abdominal Fat Ratio Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis

Jung CH, Rhee EJ, Kwon H, Chang Y, Ryu S, Lee WY

  • Endocrinol Metab.
  • 2020 Mar;35(1):165-176.
  • doi: 10.3803/EnM.2020.35.1.165
BACKGROUND: We evaluated the association of visceral-to-subcutaneous fat ratio (VSR) with nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis degree based on noninvasive serum fibrosis markers in the general population...
Epidemiology and Prognosis of Pheochromocytoma/Paraganglioma in Korea: A Nationwide Study Based on the National Health Insurance Service

Kim JH, Moon H, Noh J, Lee J, Kim SG

  • Endocrinol Metab.
  • 2020 Mar;35(1):157-164.
  • doi: 10.3803/EnM.2020.35.1.157
BACKGROUND: Pheochromocytomas and paragangliomas (PPGLs) are rare endocrine tumors originating from chromaffin cells. PPGLs are associated with a high mortality rate and several complications. To date, no epidemiological studies have...
Modification of the Tumor-Node-Metastasis Staging System for Differentiated Thyroid Carcinoma by Considering Extra-Thyroidal Extension and Lateral Cervical Lymph Node Metastasis

Kim M, Kim WG, Jeon MJ, Kim HK, Yi HS, Kim ES, Kim BH, Kim WB, Shong YK, Kang HC, Kim TY

  • Endocrinol Metab.
  • 2020 Mar;35(1):149-156.
  • doi: 10.3803/EnM.2020.35.1.149
BACKGROUND: Concerns have arisen about the classification of extra-thyroidal extension (ETE) and lateral cervical lymph node metastasis (N1b) in the 8th edition of the tumor-node-metastasis staging system (TNM-8). This study...
Comparison of the Efficacy and Safety of Insulin Detemir Administered Once Daily According to Two Titration Algorithms (3-0-3 and 2-4-6-8) in Patients with Type 2 Diabetes Mellitus

Yu HM, Park KS, Hong JH, Park KY, Lee JM, Ku BJ, Kim YJ, Oh TK

  • Endocrinol Metab.
  • 2020 Mar;35(1):142-148.
  • doi: 10.3803/EnM.2020.35.1.142
BACKGROUND: This study was conducted to compare glycaemic control with insulin detemir administered according to two titration algorithms (3-0-3 and 2-4-6-8) after 20 weeks of treatment in subjects with type...
Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma

Moon SJ, Kim JH, Kong SH, Shin CS

  • Endocrinol Metab.
  • 2020 Mar;35(1):132-141.
  • doi: 10.3803/EnM.2020.35.1.132
BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been...
Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis

Koo BK, Denenberg , Wright CM, Criqui MH, Allison MA

  • Endocrinol Metab.
  • 2020 Mar;35(1):122-131.
  • doi: 10.3803/EnM.2020.35.1.122
BACKGROUND: We investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds. METHODS: Using a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans....
Quality of Life in Patients with Papillary Thyroid Microcarcinoma According to Treatment: Total Thyroidectomy with or without Radioactive Iodine Ablation

Ahn J, Jeon MJ, Song E, Kim TY, Kim WB, Shong YK, Kim WG

  • Endocrinol Metab.
  • 2020 Mar;35(1):115-121.
  • doi: 10.3803/EnM.2020.35.1.115
BACKGROUND: Recently, there has been some controversy regarding the role of radioactive iodine (RAI) ablation in the treatment of low-risk differentiated thyroid carcinoma (DTC), especially papillary thyroid microcarcinoma (PTMC). This...
Association between Serum Free Thyroxine and Anemia in Euthyroid Adults: A Nationwide Study

Kim M, Kim BH, Lee H, Jang MH, Kim JM, Kim EH, Jeon YK, Kim SS, Kim IJ

  • Endocrinol Metab.
  • 2020 Mar;35(1):106-114.
  • doi: 10.3803/EnM.2020.35.1.106
BACKGROUND: Studies on the relationship between thyroid function and anemia in the euthyroid range are scarce. We aimed to evaluate the association between anemia and serum free thyroxine (fT4) and...
Vitamin D Deficiency at Mid-Pregnancy Is Associated with a Higher Risk of Postpartum Glucose Intolerance in Women with Gestational Diabetes Mellitus

Kim KS, Park SW, Cho YW, Kim SK

  • Endocrinol Metab.
  • 2020 Mar;35(1):97-105.
  • doi: 10.3803/EnM.2020.35.1.97
BACKGROUND: To evaluate the association between serum 25-hydroxyvitamin D (25(OH)D) at mid-pregnancy and postpartum glucose intolerance in women with gestational diabetes mellitus (GDM). METHODS: We enrolled 348 pregnant women diagnosed with...
A Brief Overview of the Epidemiology of Pheochromocytoma and Paraganglioma in Korea

Choi YM

  • Endocrinol Metab.
  • 2020 Mar;35(1):95-96.
  • doi: 10.3803/EnM.2020.35.1.95
No abstract available.
Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets

Rhee EJ

  • Endocrinol Metab.
  • 2020 Mar;35(1):85-94.
  • doi: 10.3803/EnM.2020.35.1.85
Korea is currently an aged society and is on the cusp of becoming a superaged society in a few years. The health burden of cardiovascular diseases increases with age, and...
Machine Learning Applications in Endocrinology and Metabolism Research: An Overview

Hong N, Park H, Rhee Y

  • Endocrinol Metab.
  • 2020 Mar;35(1):71-84.
  • doi: 10.3803/EnM.2020.35.1.71
Machine learning (ML) applications have received extensive attention in endocrinology research during the last decade. This review summarizes the basic concepts of ML and certain research topics in endocrinology and...
Rare PTH Gene Mutations Causing Parathyroid Disorders: A Review

Lee JH, Davaatseren M, Lee S

  • Endocrinol Metab.
  • 2020 Mar;35(1):64-70.
  • doi: 10.3803/EnM.2020.35.1.64
Since parathyroid hormone (PTH) was first isolated and its gene (PTH) was sequenced, only eight PTH mutations have been discovered. The C18R mutation in PTH, discovered in 1990, was the...
Potential Biomarkers to Improve the Prediction of Osteoporotic Fractures

Kim BJ, Lee SH, Koh JM

  • Endocrinol Metab.
  • 2020 Mar;35(1):55-63.
  • doi: 10.3803/EnM.2020.35.1.55
Osteoporotic fracture (OF) is associated with high disability and morbidity rates. The burden of OF may be reduced by early identification of subjects who are vulnerable to fracture. Although the...
Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers

Yoo SK, Song YS, Park YJ, Seo JS

  • Endocrinol Metab.
  • 2020 Mar;35(1):44-54.
  • doi: 10.3803/EnM.2020.35.1.44
Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5...
Multifaceted Actions of Succinate as a Signaling Transmitter Vary with Its Cellular Locations

Guo Y, Cho SW, Saxena D, Li X

  • Endocrinol Metab.
  • 2020 Mar;35(1):36-43.
  • doi: 10.3803/EnM.2020.35.1.36
Since the identification of succinate's receptor in 2004, studies supporting the involvement of succinate signaling through its receptor in various diseases have accumulated and most of these investigations have highlighted...

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