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Association between Serum Free Thyroxine and Anemia in Euthyroid Adults: A Nationwide Study

Ma ZF

  • Endocrinol Metab.
  • 2020 Jun;35(2):484-485.
  • doi: 10.3803/EnM.2020.35.2.484
Comparison of Serum PCSK9 Levels in Subjects with Normoglycemia, Impaired Fasting Glucose, and Impaired Glucose Tolerance

Han E, Cho NH, Moon SS, Cho H

  • Endocrinol Metab.
  • 2020 Jun;35(2):480-483.
  • doi: 10.3803/EnM.2020.35.2.480
We investigated proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations in individuals with normoglycemia, impaired fasting glucose (IFG), and impaired glucose tolerance (IGT). This was a pilot, cross-sectional study including 92...
Serotonin Regulates De Novo Lipogenesis in Adipose Tissues through Serotonin Receptor 2A

Shong KE, Oh CM, Namkung J, Park S, Kim H

  • Endocrinol Metab.
  • 2020 Jun;35(2):470-479.
  • doi: 10.3803/EnM.2020.35.2.470
Background: Obesity is defined as excessive fat mass and is a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer. Increasing energy expenditure and regulating adipose...
Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading

Hong AR, Kim K, Lee JY, Yang JY, Kim JH, Shin CS, Kim SW

  • Endocrinol Metab.
  • 2020 Jun;35(2):456-469.
  • doi: 10.3803/EnM.2020.35.2.456
Background: We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical...
Mechanisms of the Impact of Hashimoto Thyroiditis on Papillary Thyroid Carcinoma Progression: Relationship with the Tumor Immune Microenvironment

Sulaieva O, Chernenko S, Selesnov O, Nechay O, Maievskyi O, Falalyeyeva T, Kobyliak N, Tsyryuk O, Penchuk Y, Shapochka D

  • Endocrinol Metab.
  • 2020 Jun;35(2):443-455.
  • doi: 10.3803/EnM.2020.35.2.443
Background: The relationship between Hashimoto thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains uncertain. We assessed the impact of HT on the tumor immune microenvironment (TIME) in PTC. Methods: Thirty patients...
Development and Validation of a Risk Scoring System Derived from Meta-Analyses of Papillary Thyroid Cancer

Suh S, Goh TS, Kim YH, Oh SO, Pak K, Seok JW, Kim IJ

  • Endocrinol Metab.
  • 2020 Jun;35(2):435-442.
  • doi: 10.3803/EnM.2020.35.2.435
Background: The aim of this study was to develop a scoring system to stratify the risk of papillary thyroid cancer (PTC) and to select the proper management. Methods: We performed a...
Effect of Lactobacillus sakei, a Probiotic Derived from Kimchi, on Body Fat in Koreans with Obesity: A Randomized Controlled Study

Lim S, Moon JH, Shin CM, Jeong D, Kim B

  • Endocrinol Metab.
  • 2020 Jun;35(2):425-434.
  • doi: 10.3803/EnM.2020.35.2.425
Background: The increased prevalence of obesity has led to increases in the prevalence of chronic diseases worldwide. There is interest whether probiotics have an effect on obesity, but the effectiveness...
Association of Body Mass Index with the Risk of Incident Type 2 Diabetes, Cardiovascular Disease, and All-Cause Mortality: A Community-Based Prospective Study

Bae JC, Cho NH, Kim JH, Hur KY, Jin SM, Lee MK

  • Endocrinol Metab.
  • 2020 Jun;35(2):416-424.
  • doi: 10.3803/EnM.2020.35.2.416
Background: Type 2 diabetes and cardiovascular disease (CVD) are the most important sequelae of obesity and the leading cause of death. We evaluated the association between body mass index (BMI)...
Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation

Lee MK, Baek JH, Chung SR, Choi YJ, Lee YM, Kim TY, Lee JH

  • Endocrinol Metab.
  • 2020 Jun;35(2):407-415.
  • doi: 10.3803/EnM.2020.35.2.407
Background: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose...
Serum Adiponectin and Progranulin Level in Patients with Benign Thyroid Nodule or Papillary Thyroid Cancer

Kwon H, Park SE, Yun JS, Park CY

  • Endocrinol Metab.
  • 2020 Jun;35(2):396-406.
  • doi: 10.3803/EnM.2020.35.2.396
Background: Obesity is associated with thyroid cancer risk. Adiponectin has insulin-sensitizing and anti-inflammatory effects, while progranulin is associated with inflammation and tumorigenesis. We investigated serum adiponectin and progranulin levels in...
Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway

Hong OK, Lee SS, Yoo SJ, Lee MK, Kim MK, Baek KH, Song KH, Kwon HS

  • Endocrinol Metab.
  • 2020 Jun;35(2):384-395.
  • doi: 10.3803/EnM.2020.35.2.384
Background: Endothelial-to-mesenchymal transition (EndMT) contributes to inflammatory conditions inducing conversion of endothelial cells (ECs) into activated fibroblasts, promoting fibrotic diseases. Pro-inflammatory cytokine is the most potent inducer of EndMT. We...
Consistency of the Glycation Gap with the Hemoglobin Glycation Index Derived from a Continuous Glucose Monitoring System

Joung HN, Kwon HS, Baek KH, Song KH, Kim MK

  • Endocrinol Metab.
  • 2020 Jun;35(2):377-383.
  • doi: 10.3803/EnM.2020.35.2.377
Background: Discordances between glycated hemoglobin (HbA1c) levels and glycemic control are common in clinical practice. We aimed to investigate the consistency of the glycation gap with the hemoglobin glycation index...
Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments

Yang YS, Lee SY, Kim JS, Choi KM, Lee KW, Lee SC, Cho JR, Oh SJ, Kim JH, Choi SH

  • Endocrinol Metab.
  • 2020 Jun;35(2):367-376.
  • doi: 10.3803/EnM.2020.35.2.367
Background: This study assessed the proportion of risk-stratified Korean patients with dyslipidemia achieving their low-density lipoprotein cholesterol (LDL-C) targets as defined by the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS)...
Low Predictive Value of FRAX Adjusted by Trabecular Bone Score for Osteoporotic Fractures in Korean Women: A Community-Based Cohort Study

Kim H, Kim JH, Kim MJ, Hong AR, Choi H, Ku E, Lee JH, Shin CS, Cho NH

  • Endocrinol Metab.
  • 2020 Jun;35(2):359-366.
  • doi: 10.3803/EnM.2020.35.2.359
Background: The value of the Fracture Risk Assessment Tool (FRAX) and the trabecular bone score (TBS) for assessing osteoporotic fracture risk has not been fully elucidated in Koreans. We conducted...
Apolipoprotein B Levels Predict Future Development of Hypertension Independent of Visceral Adiposity and Insulin Sensitivity

Han SJ, Fujimoto WY, Kahn SE, Leonetti DL, Boyko EJ

  • Endocrinol Metab.
  • 2020 Jun;35(2):351-358.
  • doi: 10.3803/EnM.2020.35.2.351
Background: High plasma apolipoprotein B (apoB) levels have been shown to be associated with hypertension, central obesity, and insulin resistance in cross-sectional research. However, it is unclear whether apoB levels...
Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis

Cho SJ, Baek JH, Chung SR, Choi YJ, Lee JH

  • Endocrinol Metab.
  • 2020 Jun;35(2):339-350.
  • doi: 10.3803/EnM.2020.35.2.339
Background: Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis...
Glycemic Efficacy and Metabolic Consequences of an Empagliflozin Add-on versus Conventional Dose-Increasing Strategy in Patients with Type 2 Diabetes Inadequately Controlled by Metformin and Sulfonylurea

Shin Y, Moon JH, Chin HJ, Ferrannini E, Lim S

  • Endocrinol Metab.
  • 2020 Jun;35(2):329-338.
  • doi: 10.3803/EnM.2020.35.2.329
Background: We assessed the glucose-lowering efficacy of adding empagliflozin versus dose escalating existing medications in patients with uncontrolled type 2 diabetes (T2D). Methods: This was a 6-month retrospective case-control study in...
Relationships between Thigh and Waist Circumference, Hemoglobin Glycation Index, and Carotid Plaque in Patients with Type 2 Diabetes

Yoon MK, Kang JG, Lee SJ, Ihm SH, Huh KB, Kim CS

  • Endocrinol Metab.
  • 2020 Jun;35(2):319-328.
  • doi: 10.3803/EnM.2020.35.2.319
Background: This study investigated the relationships of thigh and waist circumference with the hemoglobin glycation index (HGI) and carotid atherosclerosis in patients with type 2 diabetes. Methods: This observational study included...
Subclinical Hypothyroidism Affects the Long-Term Outcomes of Patients Who Undergo Coronary Artery Bypass Grafting Surgery but Not Heart Valve Surgery

Kim H, Kong SH, Moon JH, Kim SY, Park KH, Kim JS, Choh JH, Park YJ, Lim C

  • Endocrinol Metab.
  • 2020 Jun;35(2):308-318.
  • doi: 10.3803/EnM.2020.35.2.308
Background: The aim of this study was to determine the associations between subclinical hypothyroidism (SCH) and long-term cardiovascular outcomes after coronary artery bypass grafting (CABG) or heart valve surgery (HVS). Methods:...
Effects of a Portfolio-Mediterranean Diet and a Mediterranean Diet with or without a Sterol-Enriched Yogurt in Individuals with Hypercholesterolemia

Ferro Y, Mazza E, Salvati M, Santariga E, Giampà S, Spagnuolo R, Doldo P, Pujia R, Coppola A, Gazzaruso C, Pujia A, Montalcini T

  • Endocrinol Metab.
  • 2020 Jun;35(2):298-307.
  • doi: 10.3803/EnM.2020.35.2.298
Background: A growing number of functional foods have been proposed to reduce cholesterol levels and the Portfolio Diet, which includes a combination of plant sterols, fibres, nuts, and soy protein,...

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