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Response: Serum Concentrations of Ghrelin and Leptin according to Thyroid Hormone Condition, and Their Correlations with Insulin Resistance (Endocrinol Metab 2015;30:318-25, Kyu-Jin Kim et al.)

Jung CH

  • Endocrinol Metab.
  • 2015 Dec;30(4):633-634.
  • doi: 10.3803/EnM.2015.30.4.633
No abstract available.
Letter: Serum Concentrations of Ghrelin and Leptin according to Thyroid Hormone Condition, and Their Correlations with Insulin Resistance (Endocrinol Metab 2015;30:318-25, Kyu-Jin Kim et al.)

Kim JH

  • Endocrinol Metab.
  • 2015 Dec;30(4):631-632.
  • doi: 10.3803/EnM.2015.30.4.631
No abstract available.
A Rare Manifestation of Hypothyroid Myopathy: Hoffmann's Syndrome

Lee KW, Kim SH, Kim KJ, Kim SH, Kim HY, Kim BJ, Kim SG, Choi DS

  • Endocrinol Metab.
  • 2015 Dec;30(4):626-630.
  • doi: 10.3803/EnM.2015.30.4.626
Hypothyroid myopathy is observed frequently and the resolution of the clinical manifestations of myopathy following thyroid hormone replacement is well known. However, a specific subtype of hypothyroid myopathy, Hoffmann's syndrome,...
Refractory Graves' Disease Successfully Cured by Adjunctive Cholestyramine and Subsequent Total Thyroidectomy

Yang Y, Hwang S, Kim M, Lim Y, Kim MH, Lee S, Lim DJ, Kang MI, Cha BY

  • Endocrinol Metab.
  • 2015 Dec;30(4):620-625.
  • doi: 10.3803/EnM.2015.30.4.620
The three major forms of treatment for Graves thyrotoxicosis are antithyroid drugs, radioactive iodine therapy and thyroidectomy. Surgery is the definitive treatment for Graves thyrotoxicosis that is generally recommended when...
Primary Hyperparathyroidism with Extensive Brown Tumors and Multiple Fractures in a 20-Year-Old Woman

Choi JH, Kim KJ, Lee YJ, Kim SH, Kim SG, Jung KY, Choi DS, Kim NH

  • Endocrinol Metab.
  • 2015 Dec;30(4):614-619.
  • doi: 10.3803/EnM.2015.30.4.614
A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of...
Bilateral Adrenocortical Masses Producing Aldosterone and Cortisol Independently

Lee SE, Kim JH, Lee YB, Seok H, Shin IS, Eun YH, Kim JH, Oh YL

  • Endocrinol Metab.
  • 2015 Dec;30(4):607-613.
  • doi: 10.3803/EnM.2015.30.4.607
A 31-year-old woman was referred to our hospital with symptoms of hypertension and bilateral adrenocortical masses with no feature of Cushing syndrome. The serum aldosterone/renin ratio was elevated and the...
Allgrove (Triple A) Syndrome: A Case Report from the Kashmir Valley

Misgar RA, Pala NA, Ramzan M, Wani AI, Bashir MI, Laway BA

  • Endocrinol Metab.
  • 2015 Dec;30(4):604-606.
  • doi: 10.3803/EnM.2015.30.4.604
Allgrove (Triple A) syndrome is a rare autosomal recessive disorder characterized by cardinal features of adrenal insufficiency due to adrenocorticotropic hormone (ACTH) resistance, achalasia, and alacrimia. It is frequently associated...
Selective Mitochondrial Uptake of MKT-077 Can Suppress Medullary Thyroid Carcinoma Cell Survival In Vitro and In Vivo

Starenki D, Park JI

  • Endocrinol Metab.
  • 2015 Dec;30(4):593-603.
  • doi: 10.3803/EnM.2015.30.4.593
BACKGROUND: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the rearranged during transfection (RET) proto-oncogene. Not all patients with progressive MTC respond to current therapy...
Thyroid Hormone Regulates the mRNA Expression of Small Heterodimer Partner through Liver Receptor Homolog-1

Ahn HY, Kim HH, Kim YA, Kim M, Ohn JH, Chung SS, Lee YK, Park DJ, Park KS, Moore DD, Park YJ

  • Endocrinol Metab.
  • 2015 Dec;30(4):584-592.
  • doi: 10.3803/EnM.2015.30.4.584
BACKGROUND: Expression of hepatic cholesterol 7alpha-hydroxylase (CYP7A1) is negatively regulated by orphan nuclear receptor small heterodimer partner (SHP). In this study, we aimed to find whether thyroid hormone regulates SHP...
Melanocortin 4 Receptor and Dopamine D2 Receptor Expression in Brain Areas Involved in Food Intake

Yoon YR, Baik JH

  • Endocrinol Metab.
  • 2015 Dec;30(4):576-583.
  • doi: 10.3803/EnM.2015.30.4.576
BACKGROUND: The melanocortin 4 receptor (MC4R) is involved in the regulation of homeostatic energy balance by the hypothalamus. Recent reports showed that MC4R can also control the motivation for food...
Omega-3 Polyunsaturated Fatty Acids May Attenuate Streptozotocin-Induced Pancreatic beta-Cell Death via Autophagy Activation in Fat1 Transgenic Mice

Hwang WM, Bak DH, Kim DH, Hong JY, Han SY, Park KY, Lim K, Lim DM, Kang JG

  • Endocrinol Metab.
  • 2015 Dec;30(4):569-575.
  • doi: 10.3803/EnM.2015.30.4.569
BACKGROUND: Inflammatory factors and beta-cell dysfunction due to high-fat diets aggravate chronic diseases and their complications. However, omega-3 dietary fats have anti-inflammatory effects, and the involvement of autophagy in the...
Diastolic Dysfunction Induced by a High-Fat Diet Is Associated with Mitochondrial Abnormality and Adenosine Triphosphate Levels in Rats

Kang KW, Kim OS, Chin JY, Kim WH, Park SH, Choi YJ, Shin JH, Jung KT, Lim DS, Lee SK

  • Endocrinol Metab.
  • 2015 Dec;30(4):557-568.
  • doi: 10.3803/EnM.2015.30.4.557
BACKGROUND: Obesity is well-known as a risk factor for heart failure, including diastolic dysfunction. However, this mechanism in high-fat diet (HFD)-induced obese rats remain controversial. The purpose of this study...
Characteristics of Body Composition and Muscle Strength of North Korean Refugees during South Korean Stay

Cho SW, Lee SH, Koh ES, Kim SE, Kim SJ

  • Endocrinol Metab.
  • 2015 Dec;30(4):551-556.
  • doi: 10.3803/EnM.2015.30.4.551
BACKGROUND: The aim of this study was to investigate the changes of body composition and muscle strength of North Korean refugees (NKRs) according to their duration of stay in South...
Risk Factors for Recurrence in Filipinos with Well-Differentiated Thyroid Cancer

Lo TE, Canto AU, Maningat P

  • Endocrinol Metab.
  • 2015 Dec;30(4):543-550.
  • doi: 10.3803/EnM.2015.30.4.543
BACKGROUND: The incidence of well-differentiated thyroid cancer (WDTC) has increased in recent years. Despite its excellent prognosis, increasing morbidity from recurrent diseases continues to affect long-term outcomes. Among at-risk populations,...
Economic Evaluation of Recombinant Human Thyroid Stimulating Hormone Stimulation vs. Thyroid Hormone Withdrawal Prior to Radioiodine Ablation for Thyroid Cancer: The Korean Perspective

Sohn SY, Jang HW, Cho YY, Kim SW, Chung JH

  • Endocrinol Metab.
  • 2015 Dec;30(4):531-542.
  • doi: 10.3803/EnM.2015.30.4.531
BACKGROUND: Previous studies have suggested that recombinant human thyroid stimulating hormone (rhTSH) stimulation is an acceptable alternative to thyroid hormone withdrawal (THW) when radioiodine remnant ablation is planned for thyroid...
Metabolic Health Is More Important than Obesity in the Development of Nonalcoholic Fatty Liver Disease: A 4-Year Retrospective Study

Lee MK, Rhee EJ, Kim MC, Moon BS, Lee JI, Song YS, Han EN, Lee HS, Son Y, Park SE, Park CY, Oh KW, Park SW, Lee WY

  • Endocrinol Metab.
  • 2015 Dec;30(4):522-530.
  • doi: 10.3803/EnM.2015.30.4.522
BACKGROUND: The aim of this study is to compare the risk for future development of nonalcoholic fatty liver disease (NAFLD) according to different status of metabolic health and obesity. METHODS: A...
Characterization of Patients with Type 2 Diabetes according to Body Mass Index: Korea National Health and Nutrition Examination Survey from 2007 to 2011

Lee DH, Jung KY, Park KS, Kim KM, Moon JH, Lim S, Jang HC, Choi SH

  • Endocrinol Metab.
  • 2015 Dec;30(4):514-521.
  • doi: 10.3803/EnM.2015.30.4.514
BACKGROUND: The present study aimed to investigate the clinical characteristics of type 2 diabetes mellitus (T2DM) in Korean adults according to body mass index (BMI) and to analyze the association...
Clinical Characteristics of Subjects with Sulfonylurea-Dependent Type 2 Diabetes

Min SH, Kwak SH, Cho YM, Park KS, Jung HS

  • Endocrinol Metab.
  • 2015 Dec;30(4):509-513.
  • doi: 10.3803/EnM.2015.30.4.509
BACKGROUND: Even though several oral anti-diabetic drugs (OAD) with various modes of action are replacing sulfonylurea (SU), some patients seem to be dependent on SU for adequate glycemic control. Therefore,...
Electrolyte Imbalance in Patients with Sheehan's Syndrome

Lim CH, Han JH, Jin J, Yu JE, Chung JO, Cho DH, Chung DJ, Chung MY

  • Endocrinol Metab.
  • 2015 Dec;30(4):502-508.
  • doi: 10.3803/EnM.2015.30.4.502
BACKGROUND: We investigated the prevalence of electrolyte imbalance and the relationship between serum electrolyte and anterior pituitary hormone levels in patients with Sheehan's syndrome. METHODS: In a retrospective study, we investigated...
Association of the Preoperative Neutrophil-to-ymphocyte Count Ratio and Platelet-to-Lymphocyte Count Ratio with Clinicopathological Characteristics in Patients with Papillary Thyroid Cancer

Kim SM, Kim EH, Kim BH, Kim JH, Park SB, Nam YJ, Ahn KH, Oh MY, Kim WJ, Jeon YK, Kim SS, Kim YK, Kim IJ

  • Endocrinol Metab.
  • 2015 Dec;30(4):494-501.
  • doi: 10.3803/EnM.2015.30.4.494
BACKGROUND: Several inflammatory biomarkers, especially a high preoperative neutrophil-to-lymphocyte count ratio (NLR) and platelet-to-lymphocyte count ratio (PLR), are known to be indicator of poor prognosis in several cancers. However, very...

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