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Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled

Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH

Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and...
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Folate and Homocysteine Levels during Pregnancy affect DNA Methylation in Human Placenta

Park BH, Kim YJ, Park JS, Lee HY, Ha EH, Min JW, Park HS

  • KMID: 792375
  • J Prev Med Public Health.
  • 2005 Nov;38(4):437-442.
OBJECTIVES: DNA methylation is one of the best characterized epigenetic mechanisms that play a regulatory role in genome programming and imprinting during embryogenesis. In this present study, we investigated the...
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