- Inhibitory Effect of Double Coating with Echinomycin and Hydrophobic Heparin in a Porcine Coronary In-Stent Restenosis Model
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Lim SY, Jeong MH, Sim DS, Hong YJ, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC, Moon HT, Byun Y
- KMID: 2172266
- Chonnam Med J.
- 2009 Aug;45(2):87-91.
- doi: 10.4068/cmj.2009.45.2.87
Stent thrombosis and in-stent restenosis are still major limitations of coronary stenting. Here, we report on a new type of drug-eluting stent (DES) aimed to prevent restenosis and thrombosis. The... -
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- Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins
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Wang Z, Zhang Z, Wu Y, Chen L, Luo Q, Zhang J, Chen J, Luo Z, Huang X, Cheng Y
- KMID: 1506225
- Exp Mol Med.
- 2012 Oct;44(10):615-621.
Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesis that... -
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- Confirmation of HIF-1α Independent Pathway in the Progression of HepG2 Cells by Hypoxic Condition
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Lee SW, Chong JU, Min SO, Kim KS
- KMID: 2198520
- J Liver Cancer.
- 2016 Mar;16(1):31-37.
- doi: 10.17998/jlc.2016.16.1.31
BACKGROUND/AIMS: When hepatocellular carcinoma (HCC) is exposed to hypoxic condition, HIF-1α is activated and results in angiogenesis and increased tumor burden. Although inhibition of HIF-1α may reduce tumor growth, there... -
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