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EBV-miR-BHRF1-1 Targets p53 Gene: Potential Role in Epstein-BarrVirus Associated Chronic Lymphocytic Leukemia

Xu DM, Kong YL, Wang L, Zhu HY, Wu JZ, Xia Y, Li Y, Qin SC, Fan L, Li JY, Liang JH, Xu W

Purpose The purpose of this study was to investigate the prognostic impact of Epstein-Barr virus (EBV)–microRNA (miRNA, miR)-BHRF1-1 with chronic lymphocytic leukemia (CLL) as well as role of EBV-miR-BHRF1-1 in p53 gene. Materials and...
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Single Patient Classifier Assay, Microsatellite Instability, and Epstein-Barr Virus Status Predict Clinical Outcomes in Stage II/III Gastric Cancer: Results from CLASSIC Trial

Roh CK, Choi YY, Choi S, Seo WJ, Cho M, Jang E, Son T, Kim HI, Kim H, Hyung WJ, Huh YM, Noh SH, Cheong JH

PURPOSE: Clinical implications of single patient classifier (SPC) and microsatellite instability (MSI) in stage II/III gastric cancer have been reported. We investigated SPC and the status of MSI and Epstein-Barr...
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Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells

Park JK, Seo JS, Lee SK, Chan KK, Kuh HJ

Epigenetic silencing is considered to be a major mechanism for loss of activity in tumor suppressors. Reversal of epigenetic silencing by using inhibitors of DNA methyltransferase (DNMT) or histone deacetylases...
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Epstein Barr Virus-associated Vesicular Eruptions of the Face

Cho KH

  • KMID: 2436621
  • Korean J Dermatol.
  • 2018 Jan;56(1):1-9.
Epstein Barr virus (EBV)-associated vesicular eruptions on the face have been referred to as hydroa vacciniforme or hydroa vacciniforme-like eruptions. It is well recognized that these eruptions develop as a...
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Posttransplantation lymphoproliferative disorder after pediatric solid organ transplantation: experiences of 20 years in a single center

Jeong HJ, Ahn YH, Park E, Choi Y, Yi NJ, Ko JS, Min SI, Ha JW, Ha IS, Cheong HI, Kang HG

PURPOSE: To evaluate the clinical spectrum of posttransplantation lymphoproliferative disorder (PTLD) after solid organ transplantation (SOT) in children. METHODS: We retrospectively reviewed the medical records of 18 patients with PTLD who...
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Evaluation of Real-time PCR Kits for Epstein-Barr Virus DNA Assays

Ha J, Park Y, Shim J, Kim HS

BACKGROUND: Epstein-Barr virus (EBV) is known to be the causative agent of infectious mononucleosis and EBV-related malignancies. In this study, we compared the results of three real-time PCR kits for...
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Chronic Epstein-Barr virus infection causing both benign and malignant lymphoproliferative disorders

Kwun Y, Hong SJ, Lee JS, Son DH, Seo JJ

The Epstein-Barr virus (EBV) is oncogenic and can transform B cells from a benign to a malignant phenotype. EBV infection is also associated with lymphoid interstitial pneumonia (LIP). Here, we...
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Dapsone Hypersensitivity Syndrome with EBV Reactivation

Cho JW, Lee KS, Han G

  • KMID: 1796732
  • Korean J Dermatol.
  • 2014 May;52(5):358-360.
No abstract available.
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Epstein-Barr Virus Associated Hydroa Vacciniforme-like Eruption

Cho KH

  • KMID: 2247543
  • Korean J Dermatol.
  • 2011 Sep;49(9):773-779.
Hydroa vacciniforme (HV) is a rare self-limiting disease characterized by vesicles and crust formation after sun exposure. However, cases with HV-like eruptions and severe systemic symptoms have also been described....
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Cross-linking of CD80 and CD86 Diminishes Expression of CD54 on EBV-transformed B Cells through Inactivation of RhoA and Ras

Park GB, Kim YS, Song H, Kim S, Park DM, Lee WJ, Hur DY

BACKGROUND: Epstein Barr virus (EBV) infected B cells are transformed into lymphoblastoid cell lines. Some researchers suggested some a few similarities between this process and carcinogenesis. We observed the expression...
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Significance of Epstein-Barr Virus DNA Quantitation in Donors of Hematopoietic Stem Cell Transplantation

Jung S, Lim J, Cho BS, Chae H, Kim M, Kim Y, Han K, Lee JW, Min WS

BACKGROUND: Epstein-Barr virus (EBV) is a well-known causative agent of various diseases including post-transplant lymphoproliferative disorders. Although the level of EBV viral load in donors is expected to have a...
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A Case of Epstein-Barr-Virus-Associated Lymphocytic Interstitial Pneumonia

Kim JH, Oh SH, Song YW, Kim BJ, Yu JH, Hwang JE, Hong SJ

  • KMID: 1474542
  • Pediatr Allergy Respir Dis.
  • 2009 Sep;19(3):307-313.
Lymphocytic interstitial pneumonia (LIP) is a benign lymphoproliferative disorder characterized histologically by diffuse infiltration with predominantly mature lymphocytes, plasma cells and reticuloendothelial cells in the alveolar septae and along the...
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Epstein-Barr virus-transformation of B-cell lines in ovarian cancer patients: feasibility of genomic storage for unlimited use

Kong SY, Kang S

OBJECTIVE: The aim of the current study is to test whether immortalized B-lymphocyte cell line via Ebstein-Barr virus (EBV) transformation is feasible and can be an unlimited source of genome...
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A case of concomitant epstein-barr virus-induced hepatitis on chronic autoimmune hepatitis

Jung JG, Moon DG, Yang HJ, Kwon JH, Kang JH, Jung ES, Yoon SK

  • KMID: 2256198
  • Korean J Med.
  • 2008 Jun;74(6):658-662.
Autoimmune hepatitis (AIH), a rare cause of chronic liver disease in Korea, is a chronic, predominantly periportal hepatitis characterized by hypergammaglobulinemia, tissue autoantibodies, and responsiveness to immunosuppressive therapy. Here we...
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Quantifing the Circulating Epstein-Barr Virus (EBV) DNA to Monitor a Case of Aggressive Natural Killer Cell Leukemia

Yi SY, Kim HS, Jun HJ, Yang JH, Ko YH, Ki CS, Kim WS

Epstein-Barr virus (EBV) infection is associated with various lymphoproliferative diseases, including Hodgkin lymphoma, extranodal NK/T cell lymphoma, aggressive NK cell leukemia, Burkitt lymphoma and post-transplant lymphoproliferative disorder. In the recent...
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Bone Marrow Fibrin-Ring Granuloma: Review of 24 Cases

Chung HJ, Chi HS, Cho YU, Jang S, Park CJ

BACKGROUND: Fibrin-ring granuloma (FRG), which can be found in bone marrow or the liver, is a subtype of epithelioid granuloma characterized by a central fat vacuole and annular peripheral...
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Association of Epstein-Barr Virus and Head and Neck Cancer in an Endemic Area

Kim AY, Roh JL, Kim JM, Rha KS, Park CI

  • KMID: 2276718
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 Mar;50(3):235-239.
BACKGROUND AND OBJECTIVES: A number of reports have suggested that Epstein-Barr virus (EBV) is associated with different forms of head and neck cancers (HNC) such as nasopharyngeal carcinoma, NK/T cell...
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Clinical review of Epstein-Barr virus viremia in Korean children by using real-time PCR

Ko IY, Suh JS, Kim HM, Sohn JH, Yeh BI, Lee TJ, Kim DS

PURPOSE: We investigated clinical characteristics of real-time PCR proven EBV viremia patients who were not serologically diagnosed but clinically suspected, and compared it to serologically proven EBV infected patients. METHODS: The...
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Fatal Infectious Mononucleosis: A case report

Lee SA, Yim HE, You YY, Kim JH

  • KMID: 2250429
  • Korean J Leg Med.
  • 2007 Nov;31(2):188-191.
Infectious mononucleosis(IM) is a benign self-limiting disease and result from a polyclonal B cell proliferation secondary to Epstein-Barr virus (EBV) infections. The infection is controlled by cytotoxic T cells triggered...
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A Case of Diffuse Large B-cell Lymphoma in a Kidney Transplant Recipient

Byun SW, Park HW, Song JH, Oh JS, Kim EH, Huh JR, Suh C, Park SK

  • KMID: 1337416
  • Korean J Nephrol.
  • 2006 Sep;25(5):871-876.
Posttransplant lymphoproliferative disorders (PTLD) is an infrequent but serious complication of transplantation. Previous studies have suggested the terms of reference, "early PTLD" (referring to PTLD that occurs within 1 year...
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