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The clinicopathological relationship of E2F-1 and Ki-67 expression in endometrial cancer

Chong HI, Baek YJ, Jang HJ, Suh DS, Yoon MS, Choi KU

  • KMID: 2273690
  • Korean J Obstet Gynecol.
  • 2009 Feb;52(2):228-236.
OBJECTIVE: The aim of this study was to evaluate the correlation of E2F-1 and Ki-67 expression with clinicopathological prognostic factors. METHODS: Retrospectively, endometrial cancer slide samples (n=71) were analyzed. E2F-1 and...
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Rb pathway alteration and E2F-1 expression in epithelial ovarian cancer

Kim SH, Moon SH, Shin SI, Suh DS, Yoon MS, Choi KU

  • KMID: 2244533
  • Korean J Gynecol Oncol.
  • 2007 Dec;18(4):299-307.
OBJECTIVE: To evaluate the clinicopathological implications of Rb pathway alteration and E2F-1 expression in Epithelial ovarian cancer using immunohistochemical staining. METHODS: Tissue samples (n=72) were collected after staging operation between...
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A High Thymidylate Synthase Expression is Related to Better Outcome for Advanced Gastric Cancer Patients Treated with 5-FU Chemotherapy after Curative Resection

Cho MY, Yi SY, Eom MS, Zhang SP, Kim HS, Lee JI, Kim DS

  • KMID: 2277682
  • Korean J Pathol.
  • 2006 Apr;40(2):128-136.
BACKGROUND: The expressions of thymidylate synthase (TS), E2F-1, pRb, and p53 are correlated with DNA synthesis. The significance of their expressions is still controversial for predicting the outcome of 5-fluorouracil...
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Correlation of C-erbB-2 Oncogene Amplification by Chromogenic in situ Hybridization and Expressions of Cell Cycle Regulatory Proteins in Infiltrating Duct Carcinoma of the Breast

Park BK, Kim BG, Cha SJ, Park SJ, Lim HM, Park SI, Lee TJ

  • KMID: 2210285
  • J Korean Surg Soc.
  • 2006 Jan;70(1):14-24.
PURPOSE: Gene amplification and/or over-expression of the c-erbB-2 are linked with poor prognosis in breast cancer. There has been only a few reports about the connection of c-erbB-2 oncogene amplification...
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Expression of p16(INK4A), Rb and E2F-1 Proteins in Colorectal Carcinoma

Kim SS, Lee TJ, Kim BG, Cha SJ, Park SJ, Lim HM, Park SI

  • KMID: 2004529
  • J Korean Surg Soc.
  • 2003 Aug;65(2):119-125.
PURPOSE: An altered cell cycle regulation may underline the development and progression of human malignancies. The purpose of this study was to determine whether the degree of p16(INK4A), Rb and...
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The Immunohistochemical Expression of E2F-1 Protein and DNA Topoisomerase II-alpha E2F-1 Protein in Colorectal Cancer and Their Relationship with Clinicopathologic Factors

Hwang SI, Lee TJ, Park YG, Ji GC, Lee JH, Chang IT, Park SI

  • KMID: 2004546
  • J Korean Surg Soc.
  • 2003 Jul;65(1):35-41.
PURPOSE: E2F-1 is a transcriptor that converts G1 to S in the cell cycle, and Topoisomerase II-alpha is a key enzyme in the metabolism of DNA, and an indicator of...
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The Immunohistochemical Expression of DNA Topoisomerase II-alpha and E2F-1 in the Breast Carcinoma and Their Relationship with Clinicopathologic Factors

Kim HY, Lim HM, Lee TJ, Park SJ, Cha SJ, Kim BG

  • KMID: 2096039
  • J Korean Surg Soc.
  • 2003 Feb;64(2):93-100.
PURPOSE: Clinical courses of breast cancer are very different, and concern for finding a predictable marker of breast carcinomas has increased. This study focused on the relationship between the expressions...
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Expression of Cell Cycle Regulatory and Apoptosis-related Proteins in Etoposide-treated Human Skin Fibroblast

Cho JW, Suh MH

  • KMID: 2007130
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):77-83.
PURPOSE: This study was designed to investigate effect of the etoposide on expression of cell cycle regulatory proteins and apoptosis-related proteins in human skin fibroblast (HSF). MATERIALS AND METHODS: HSF cells...
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p53 gene transfer does not enhance E2F-1-mediated apoptosis in human colon cancer cells

Draus JM, Elliott MJ, Atienza C, Stilwell A, Wong SL, Dong Y, Yang H, McMasters

  • KMID: 1457532
  • Exp Mol Med.
  • 2001 Dec;33(4):209-219.
E2F-1 and p53 are sequence specific transcription factors that are intimately involved in the regulation of the cell cycle. In addition to their role in cell cycle control, both E2F-1...
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