- Smad3 deficiency accelerates tongue wound healing via epithelial cell-extracellular matrix interactions
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Taguchi C, Sato F, Wang C, Nakamura S, Oikawa K, Bhawal UK, Okada H, Arikawa K
- KMID: 2537675
- Oral Biol Res.
- 2022 Dec;46(4):141-149.
- doi: 10.21851/obr.46.04.202212.141
Aberrant wound closure occurs in a broad range of wounds and scars, and the altered regulation of transcription factors in wound areas can account for both of those conditions. This... -
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- Epithelial-Mesenchymal Transition-Inducing Factors Involved in the Progression of Lung Cancers
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Nam MW, Kim CW, Choi KC
- KMID: 2529886
- Biomol Ther.
- 2022 May;30(3):213-220.
- doi: 10.4062/biomolther.2021.178
Although there have been advances in cancer therapy and surgical improvement, lung cancer has the lowest survival rate (19%) at all stages. This is because most patients are diagnosed with... -
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- miR-200c-141 Enhances Sheep Kidney Cell Reprogramming into Pluripotent Cells by Targeting ZEB1
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Zhang Y, He Y, Wu P, Hu S, Zhang Y, Chen C
- KMID: 2522561
- Int J Stem Cells.
- 2021 Nov;14(4):423-433.
- doi: 10.15283/ijsc21080
Background and Objectives: Sheep-induced pluripotent stem cells (siPSCs) have low reprogramming efficiency, thereby hampering their use in biotechnology and agriculture. Several studies have shown that some microRNAs play an important... -
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- Role of E-cadherin and cyclin D1 as predictive markers of aggression and clonal expansion in head and neck squamous cell carcinoma
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Shergill K, Sen A, Pillai HJ
- KMID: 2419234
- J Korean Assoc Oral Maxillofac Surg.
- 2018 Aug;44(4):182-190.
- doi: 10.5125/jkaoms.2018.44.4.182
OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Inconsistency in various histopathologic features for predicting nodal metastasis and overall prognosis and a better... -
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- Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors
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Park BS, Kil JJ, Kang HM, Yu SB, Park DB, Park JA, Kim IR
- KMID: 2437357
- Int J Oral Biol.
- 2018 Jun;43(2):69-76.
- doi: 10.11620/IJOB.2018.43.2.069
Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms... -
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- Feeder Cells Free Rabbit Oral Mucosa Epithelial Cell Sheet Engineering
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Oliva J, Ochiai K, Florentino A, Bardag-Gorce F, Wood A, Niihara Y
- KMID: 2411880
- Tissue Eng Regen Med.
- 2018 Jun;15(3):321-332.
- doi: 10.1007/s13770-017-0108-4
The optimal cell culture method of autologous oral mucosal epithelial cell sheet is not well established for a safe transplantation on to the patients' ocular surface. Animal serum and 3T3... -
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- Prognosis of Pregnancy-Associated Gastric Cancer: An Age-, Sex-, and Stage-Matched Case-Control Study
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Song MJ, Park YS, Song HJ, Park SJ, Ahn JY, Choi KD, Lee GH, Jung HY, Yook JH, Kim BS
- KMID: 2412070
- Gut Liver.
- 2016 Sep;10(5):731-738.
- doi: 10.5009/gnl15323
BACKGROUND/AIMS: Pregnancy-associated gastric cancer is a rare condition. This case-control study was performed to identify the clinicopathological features and prognostic factors of pregnancy-associated gastric cancer. METHODS: All consecutive patients who presented... -
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- Hypoxia Increases Epithelial Permeability in Human Nasal Epithelia
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Min HJ, Kim TH, Yoon JH, Kim CH
- KMID: 2450360
- Yonsei Med J.
- 2015 May;56(3):825-831.
- doi: 10.3349/ymj.2015.56.3.825
PURPOSE: The nasal mucosa is the first site to encounter pathogens, and it forms continuous barriers to various stimuli. This barrier function is very important in the innate defense mechanism.... -
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- The Epithelial-Mesenchymal Transition and E-cadherin and Vimentin Expression in Basal Cell Carcinoma and Squamous Cell Carcinoma
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Kim YU, Kim KJ, Heo EP
- KMID: 2246223
- Korean J Dermatol.
- 2015 Feb;53(2):96-105.
BACKGROUND: The epithelial-mesenchymal transition (EMT) in epithelial tumor cells plays a key role in tumor invasion and metastasis. The reduction or loss of E-cadherin and the acquisition of vimentin are... -
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- Clinical Significance of Aberrant Wnt7a Promoter Methylation in Human Non-Small Cell Lung Cancer in Koreans
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Kim TH, Moon JY, Kim SH, Paik SS, Yoon HJ, Shin DH, Park SS, Sohn JW
- KMID: 2129645
- J Korean Med Sci.
- 2015 Feb;30(2):155-161.
- doi: 10.3346/jkms.2015.30.2.155
The Wnt signaling pathway has regulatory roles in cell proliferation, differentiation, and polarity. Aberrant Wnt pathway regulation can lead to abnormal cell proliferation and cancer, and loss of Wnt7a expression... -
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- Expression of E-cadherin in pig kidney
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Lee SY, Han SM, Kim JE, Chung KY, Han KH
- KMID: 1712303
- J Vet Sci.
- 2013 Dec;14(4):381-386.
- doi: 10.4142/jvs.2013.14.4.381
E-cadherin is a cell adhesion molecule that plays an important role in maintaining renal epithelial polarity and integrity. The purpose of this study was to determine the exact cellular localization... -
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- Bacteroides fragilis Toxin Induces IL-8 Secretion in HT29/C1 Cells through Disruption of E-cadherin Junctions
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Hwang S, Gwon SY, Kim MS, Lee S, Rhee KJ
- KMID: 1493616
- Immune Netw.
- 2013 Oct;13(5):213-217.
- doi: 10.4110/in.2013.13.5.213
Enterotoxigenic Bacteroides fragilis (ETBF) is a human gut commensal bacteria that causes inflammatory diarrhea and colitis. ETBF also promotes colorectal tumorigenesis in the Min mouse model. The key virulence factor... -
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- Prostaglandin E2 and Interleukin-1beta Reduce E-cadherin Expression by Enhancing Snail Expression in Gastric Cancer Cells
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Jee YS, Jang TJ, Jung KH
- KMID: 1782129
- J Korean Med Sci.
- 2012 Sep;27(9):987-992.
- doi: 10.3346/jkms.2012.27.9.987
Inflammation is closely related to the progression of cancer as well as tumorigenesis. Here, we investigated the effect of prostaglandin E2 (PGE2) and interleukin-1beta (IL-1beta) on E-cadherin expression in SNU719... -
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- Role of Keratinocytes in the Development of Vitiligo
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Lee AY
- KMID: 2434675
- Ann Dermatol.
- 2012 May;24(2):115-125.
Vitiligo is an acquired depigmentary disorder of the skin that results from the loss of functioning epidermal melanocytes. Most studies on vitiligo have concentrated on the abnormality of melanocytes rather... -
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- Immunohistochemical Study for the Syndecan-1, E-cadher in and Beta-catenin Expressions in Epidermal Tumors
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Shin BS, Choi KC, Kim HR, Kim MS
- KMID: 2247585
- Korean J Dermatol.
- 2011 Apr;49(4):309-317.
BACKGROUND: Syndecan-1, E-cadherin and beta-catenin are cell adhesion molecules that are primarily expressed on the surface of adult epithelial cells. The expressions of them appear to be inversely correlated with... -
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- Clinicopathologic significance of the expression of Snail in hepatocellular carcinoma
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Woo HY, Min AL, Choi JY, Bae SH, Yoon SK, Jung CK
- KMID: 1105509
- Korean J Hepatol.
- 2011 Mar;17(1):12-18.
- doi: 10.3350/kjhep.2011.17.1.12
BACKGROUND/AIMS: E-cadherin is involved in intercellular binding and cellular polarity formation. Snail is a key regulator of the epithelial-mesenchymal transition and is closely associated with tumor invasiveness due to its... -
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- Expression of E-cadherin, beta-catenin, Cdx2 and MMP7 in pT2 and N1/N2 Gastric Cancer: Relationship with Tumor Recurrence within 2-Year Period
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Kim JH, Eom DY, Kim CW, Choi NK, Kwak JH, Choi GM, Jang HJ, Han MS
- KMID: 2096616
- J Korean Surg Soc.
- 2011 Jan;80(1):29-35.
- doi: 10.4174/jkss.2011.80.1.29
PURPOSE: The aim of this study was to examine the expression of E-cadherin, beta-catenin, Cdx2, MMP7 in gastric cancer and to evaluate the clinical significance of these molecules in tumor... -
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- Expression of E-cadherin, Heat Shock Protein 47, Transforming Growth Factor beta1 and C4d in Chronic Allograft Nephropathy
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Chun KW, Park JH, Jung JC, Kim DJ, Park SG, Kim JS, Nam ES, Hyun SJ, Lee S
- KMID: 2324195
- J Korean Soc Transplant.
- 2010 Dec;24(4):298-305.
BACKGROUND: Chronic allograft nephropathy (CAN), which causes graft failure, is related to tubular atrophy and interstitial fibrosis. E-cadherin is a well-known epithelial marker and heat shock protein (HSP)-47 is a... -
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- Epithelial-mesenchymal transition in osteogenic sarcoma of the neck following oral squamous cell carcinoma
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Kim HS, Kim NH, Han SH, Cha IH, Seo DJ, Park W, Yook JI, Kim HJ
- KMID: 2189944
- J Korean Assoc Oral Maxillofac Surg.
- 2010 Jun;36(3):172-176.
- doi: 10.5125/jkaoms.2010.36.3.172
Postirradiation extraosseous osteogenic sarcomas are uncommon in the head and neck, despite the extensive use of high-dose radiation. It has been described as de novo radiation-induced neoplasm. We present a... -
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- Cyclooxygenase (COX)-1, Cyclooxygenase (COX)-2 and E-cadherin Expression in Colorectal Cancer Patients with Hepatic Metastasis
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Joo SH, Kim BS, Choi SI, Song JY, Lee KY, Kim YW, Kim GY, Lee SH, Lee SM, Hong SW
- KMID: 2211946
- J Korean Surg Soc.
- 2010 Mar;78(3):177-183.
- doi: 10.4174/jkss.2010.78.3.177
PURPOSE: Recent studies have shown that cyclooxygenase (COX)-2 may be involved in colorectal carcinogenesis. In this study, we evaluate the differences of COX-2 expression in patients with synchronous and metachronous... -
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