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Effect of Ginseng on the Expression of the Onco-suppressor Gene p21in Human Breast-Cancer Cell Lines

Kang SS, Duda RB

  • KMID: 2095749
  • J Korean Surg Soc.
  • 1999 Dec;57(6):782-788.
BACKGROUND: Some reports have indicated that ginseng might have an inhibitory effect on tumorogenesis. The p21 protein, a universal cell-cycle inhibitor, directly binds cyclin-CDK complexes. The aim of this study...
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American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines

Duda RB, Kang SS, Archer SY, Meng S, Hodin RA

American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle...
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