- Recent Progress in Understanding the Conformational Mechanism of Heterotrimeric G Protein Activation
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Duc NM, Kim HR, Chung KY
- KMID: 2367615
- Biomol Ther.
- 2017 Jan;25(1):4-11.
- doi: 10.4062/biomolther.2016.169
Heterotrimeric G proteins are key intracellular coordinators that receive signals from cells through activation of cognate G protein-coupled receptors (GPCRs). The details of their atomic interactions and structural mechanisms have... -
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- Comprehensive Analysis of Non-Synonymous Natural Variants of G Protein-Coupled Receptors
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Kim HR, Duc NM, Chung KY
- KMID: 2429048
- Biomol Ther.
- 2018 Mar;26(2):101-108.
- doi: 10.4062/biomolther.2017.073
G protein-coupled receptors (GPCRs) are the largest superfamily of transmembrane receptors and have vital signaling functions in various organs. Because of their critical roles in physiology and pathology, GPCRs are... -
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