- Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin
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Zhang HY, Du ZX, Liu BQ, Gao YY, Meng X, Guan Y, Deng WW, Wang HQ
- KMID: 1123811
- Exp Mol Med.
- 2009 May;41(5):362-369.
- doi: 10.3858/emm.2009.41.5.041
TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resistant to... -
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- Antisurvivin oligonucleotides inhibit growth and induce apoptosis in human medullary thyroid carcinoma cells
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Du ZX, Zhang HY, Gao DX, Wang HQ, Li YJ, Liu GL
- KMID: 1094148
- Exp Mol Med.
- 2006 Jun;38(3):230-240.
Suvivin is a novel member of the inhibitor of apoptosis protein (IAP) family, which is known to be over-expressed in various carcinomas and associated with their biologically aggressive characteristics. The... -
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