Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

10 results
Display

Natural radioprotectors and their impact on cancer drug discovery

Kuruba V, Gollapalli P

Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a number of cancers the use of chemotherapy has become standard practice. Chemotherapy is a use...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
From Bench to Market: Preparing Human Pluripotent Stem Cells Derived Cardiomyocytes for Various Applications

Moon SH, Bae D, Jung TH, Chung EB, Jeong YH, Park SJ, Chung HM

Human cardiomyocytes (CMs) cease to proliferate and remain terminally differentiated thereafter, when humans reach the mid-20s. Thus, any damages sustained by myocardium tissue are irreversible, and they require medical interventions...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Discovery of a New DNA Gyrase A Inhibitor, 4-[(1-methyl-6-nitroquinolin-1-ium-4-yl)amino]-N-[4-[(1-methylpyridin-1-ium-4-yl)amino]phenyl]benzamide

Seo I, Suh SI, Suh MH, Baek WK

Escherichia coli (E. coli) is a clinically important causative organism that can lead to urinary tract infections. Quinolone antibiotics are among the first-line treatments for urinary tract infections. However, the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery

Park SJ, Im DS

Initial discovery on sphingosine 1-phosphate (S1P) as an intracellular second messenger was faced unexpectedly with roles of S1P as a first messenger, which subsequently resulted in cloning of its G...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors

Naqvi AA, Anjum F, Khan FI, Islam A, Ahmad F, Hassan MI

Helicobacter pylori is a Gram-negative bacteria that is responsible for gastritis in human. Its spiral flagellated body helps in locomotion and colonization in the host environment. It is capable of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139

Islam MS, Shahik SM, Sohel M, Patwary NI, Hasan MA

In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetically Engineered Mouse Models for Drug Development and Preclinical Trials

Lee H

  • KMID: 2170618
  • Biomol Ther.
  • 2014 Jul;22(4):267-274.
Drug development and preclinical trials are challenging processes and more than 80% to 90% of drug candidates fail to gain approval from the United States Food and Drug Administration. Predictive...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Natural Product-Derived Drugs for the Treatment of Inflammatory Bowel Diseases

Joo YE

Natural products have been used as drugs for millennia, and the therapeutic potential of natural products has been studied for more than a century. Since the mid-1880s, approximately 60% of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Intercellular Lipid Mediators and GPCR Drug Discovery

Im DS

  • KMID: 2170658
  • Biomol Ther.
  • 2013 Nov;21(6):411-422.
G-protein-coupled receptors (GPCR) are the largest superfamily of receptors responsible for signaling between cells and tissues, and because they play important physiological roles in homeostasis, they are major drug targets....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Evaluation of Advanced Structure-Based Virtual Screening Methods for Computer-Aided Drug Discovery

Lee HS, Choi JW, Yoon SJ

  • KMID: 2166251
  • Genomics Inform.
  • 2007 Mar;5(1):24-29.
Computational virtual screening has become an essential platform of drug discovery for the efficient identification of active candidates. Moleculardocking, a key technology of receptor-centric virtual screening, is commonly used to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr