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Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus

Ito T, Hiramatsu

Methicillin-resistant Staphylococcus aureus (MRSA) produces specific penicillin-binding protein, PBP2', which shows remarkably low affinities to most beta-lactam antibiotics except those such as penicillin G and ampicillin. The region surrounding mecA...
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Emergence and spread of antimicrobial resistance of Streptococcus pneumoniae in Korea

Song JH

Pneumococcal resistance has become a global issue during the past three decades. One of the major foci of pneumococcal resistance worldwide is the Asian region including Korea, Japan, and Hong...
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Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells

Kim SH, Yeo GS, Lim YS, Kang CD, Kim CM, Chung BS

  • KMID: 754993
  • Exp Mol Med.
  • 1998 Jun;30(2):87-92.
MDR1 promoter has been shown to contain heat shock elements (HSE), and it has been reported that FM3A/M and P388/M MDR cells show a constitutively activated heat shock factor (HSF), suggesting that...
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