- Development of Clevudine Resistance after Switching from Lamivudine in a Patient with Chronic Hepatitis B
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Koh KH, Kang CJ, Kim DH, Choi YW, Kim MJ, Cheong JY, Cho SW
- KMID: 783106
- Korean J Gastroenterol.
- 2008 Nov;52(5):325-328.
Clevudine is a nucleoside analog of the unnatural beta-L configuration which has potent antiviral activity against hepatitis B virus (HBV). Clevudine is expected to have similar pattern of resistance profile... -
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- Management of Antiviral-Resistant Chronic Hepatitis B Virus Infection
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Yim HJ
- KMID: 1767539
- Korean J Gastroenterol.
- 2008 Jun;51(6):346-359.
Substantial progress has been made in the treatment of chronic hepatitis B during the past decade. Nucleos(t)ide analogues are now widely used due to their convenience, less side effects, and... -
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- High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B
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Chae HB, Kim MJ, Seo EG, Choi YH, Lee HS, Han JH, Yoon SM, Park SM, Youn SJ
- KMID: 1372654
- Korean J Hepatol.
- 2012 Mar;18(1):75-83.
- doi: 10.3350/kjhep.2012.18.1.75
BACKGROUND/AIMS: Newly developed and potent antiviral agents suffer from the problem of drug resistance. Multidrug resistance is a major impediment in the treatment of patients with chronic hepatitis B (CHB).... -
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- Analysis of Reverse Transcriptase Gene Mutations in the Hepatitis B Virus at a University Hospital in Korea
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Lee AJ, Lee CH, Jeon CH
- KMID: 1791925
- Ann Lab Med.
- 2014 May;34(3):230-234.
- doi: 10.3343/alm.2014.34.3.230
BACKGROUND: Most mutations in the reverse transcriptase (RT) gene of the hepatitis B virus (HBV) are related to resistance to antiviral agents. Cross-sectional studies on the mutations of this gene... -
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- Management of Antiviral Resistance in Chronic Hepatitis B
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Lim YS
- KMID: 2412184
- Gut Liver.
- 2017 Mar;11(2):189-195.
- doi: 10.5009/gnl15562
The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint... -
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- Two Cases of Multidrug-Resistant Human Immunodeficiency Virus Infection Treated with Atazanavir and Lopinavir/Ritonavir Combination Therapy
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Choi H, Jeong SJ, Lee HS, Chin BS, Choi SH, Han SH, Kim MS, Kim CO, Choi JY, Song YG, Kim JM
- KMID: 1785841
- J Korean Med Sci.
- 2008 Aug;23(4):737-739.
- doi: 10.3346/jkms.2008.23.4.737
The combination of atazanavir (ATV) and lopinavir/ritonavir (LPV/RTV) with nucleoside reverse transcriptase inhibitors (NRTI) has been used as a salvage regimen for human immunodeficiency virus (HIV)-positive patients. In this paper,... -
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