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Antifungal Resistance in Yeasts and Filamentous Fungi

Shin JH

The incidence of invasive fungal infection has increased worldwide along with the increasing population of high risk patients. Recently developed antifungal agents, such as second-generation triazoles and echinocandins, provide the...
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Mechanisms of Antifungal Drug Resistance in Pathogenic Fungi

Lee MK

  • KMID: 1611046
  • Korean J Clin Microbiol.
  • 2003 Sep;6(2):103-108.
No abstract available.
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Candida albicans Biofilm Formation and Pathophysiology

Moon SM, Park K, Kim YS, Woo JH

  • KMID: 1458584
  • Korean J Med Mycol.
  • 2010 Sep;15(3):116-123.
Candida species are frequently found in the normal microorganism of humans, which facilitates their encounter with most implanted biomaterials and host surfaces. Medical devices such as stents, prostheses, implants and...
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A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans

Lee KT, Kwon H, Lee D, Bahn YS

  • KMID: 2312723
  • Mycobiology.
  • 2014 Mar;42(1):52-58.
A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been identified as one of the gromwell plant extract-responsive genes in Cryptococcus neoformans. Ysa1 is known to control intracellular concentrations...
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Trend of Prevalence and Antifungal Drug Resistance of Candida Species Isolated from Candidemia Patients at a Tertiary Care Hospital During Recent Two Decades

Kim D, Hwang GY, Yoo G, Kim J, Uh Y

BACKGROUND: Candidemia has increased with an increasing number of people in the high risk group and so has become more important. This study was conducted to investigate the isolation rate...
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Species-Specific Differences in Rhodamine 6G Accumulation of Candida Isolates Detected by Flow Cytometric Analysis

Moon CJ, Shin JH, Kim DW, Kee SJ, Kim SH, Shin MG, Suh SP, Ryang DW

BACKGROUND: Fluorescent dye Rhodamine 6G (R6G) is a substrate of multidrug resistance pumps and its accumulation is reduced in some azole-resistant Candida isolates with the upregulation of multidrug efflux transporter...
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Species Distribution and Antifungal Susceptibilities of Yeast Clinical Isolates from Three Hospitals in Korea, 2001 to 2007

Lee MK, Yong D, Kim M, Kim MN, Lee K

BACKGROUND: We utilized results from the ARTEMIS DISK Global Antifungal Surveillance Program to evaluate the species distribution and fluconazole and voriconazole susceptibilities of yeast isolates from clinical specimens in South...
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In Vitro Fluconazole and Voriconazole Susceptibilities of Candida Bloodstream Isolates in Korea: Use of the CLSI and EUCAST Epidemiological Cutoff Values

Jang MJ, Shin JH, Lee WG, Kim MN, Lee K, Lee HS, Lee MK, Chang CL, Jang HC, Song ES, Kim SH, Shin MG, Suh SP, Ryang DW

BACKGROUND: At present, the clinical breakpoints (CBPs) of both fluconazole and voriconazole are available only for 3 common Candida species in the Clinical and Laboratory Standards Institute (CLSI) and the...
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Microorganisms Isolated from Blood Cultures and Their Antimicrobial Susceptibility Patterns At a University Hospital During 1994-2003

Koh EM, Lee SG, Kim CK, Kim M, Yong D, Lee K, Kim JM, Kim DS, Chong Y

BACKGROUND: Blood culture is important for the determination of the etiologic agent of bacteremia. Analysis of blood culture results and antimicrobial susceptibility trend can provide clinicians with relevant information...
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Species Distribution and Susceptibility to Azole Antifungals of Candida Bloodstream Isolates from Eight University Hospitals in Korea

Lee JS, Shin JH, Lee K, Kim MN, Shin BM, Uh Y, Lee WG, Lee HS, Chang CL, Kim SH, Shin MG, Suh SP, Ryang DW

PURPOSE: The incidence of Candida bloodstream infections (BSI) has increased over the past two decades. The rank order of occurrence and the susceptibility to antifungals of the various Candida...
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In Vitro Susceptibilities of Clinical Isolates of Aspergillus Species against Echinocandins

Lee JS, Shin JH, Jung SI, Park KH, Choi HW, Cho D, Kee SJ, Kim SH, Shin MG, Suh SP, Ryang DW

  • KMID: 2170202
  • Infect Chemother.
  • 2007 Jun;39(3):151-158.
BACKGROUND: Echinocandins are a new class of antifungal agents with potent in vitro and in vivo activities against Aspergillus species. We investigated the in vitro activity of caspofungin and micafungin...
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