- Rectal Mechano-sensory Function in Patients with Carcinoid Diarrhea
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Gregersen , Brock C, Haase AM, Laurberg S, Drewes AM, Grønbæk , Krogh K
- KMID: 2203580
- J Neurogastroenterol Motil.
- 2016 Apr;22(2):264-271.
- doi: 10.5056/jnm15113
BACKGROUND/AIMS: In patients with neuroendocrine tumors, excessive production of serotonin and other amines may cause the carcinoid syndrome, which is mainly characterized by diarrhea and flushing. Little is known about... -
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- The Impact of Opioid Treatment on Regional Gastrointestinal Transit
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Poulsen JL, Nilsson M, Brock C, Sandberg T, Krogh K, Drewes AM
- KMID: 2203582
- J Neurogastroenterol Motil.
- 2016 Apr;22(2):282-291.
- doi: 10.5056/jnm15175
BACKGROUND/AIMS: To employ an experimental model of opioid-induced bowel dysfunction in healthy human volunteers, and evaluate the impact of opioid treatment compared to placebo on gastrointestinal (GI) symptoms and motility... -
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- Esophageal Acid Clearance During Random Swallowing Is Faster in Patients with Barrett's Esophagus Than in Healthy Controls
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Lottrup C, Krarup AL, Gregersen , Ejstrud P, Drewes AM
- KMID: 2433455
- J Neurogastroenterol Motil.
- 2016 Oct;22(4):630-642.
- doi: 10.5056/jnm16019
BACKGROUND/AIMS: Impaired esophageal acid clearance may be a contributing factor in the pathogenesis of Barrett’s esophagus. However, few studies have measured acid clearance as such in these patients. In this... -
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- Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone
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Olesen AE, Grønlund , Mark EB, Krogh K, Frøkjær , Drewes AM
- KMID: 2460489
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):602-610.
- doi: 10.5056/jnm18079
BACKGROUND/AIMS: Opioids cause gastrointestinal (GI) dysmotility, decrease gut secretion, and affect gut sphincters. Symptoms of opioid-induced bowel dysfunction may be alleviated by peripherally acting opioid antagonists like naloxegol, but detailed... -
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- Gastric Emptying Time and Volume of the Small Intestine as Objective Markers in Patients With Symptoms of Diabetic Enteropathy
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Klinge MW, Sutter N, Mark EB, Haase AM, Borghammer P, Schlageter V, Lund S, Fleischer J, Knudsen K, Drewes AM, Krogh K
- KMID: 2517533
- J Neurogastroenterol Motil.
- 2021 Jul;27(3):390-399.
- doi: 10.5056/jnm19195
Background/Aims Patients with diabetes mellitus (DM) often suffer from gastrointestinal (GI) symptoms, but these correlate poorly to established objective GI motility measures. Our aim is to perform a detailed evaluation of... -
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- Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350
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Poulsen JL, Mark EB, Brock C, Frøkjær , Krogh K, Drewes AM
- KMID: 2417279
- J Neurogastroenterol Motil.
- 2018 Jan;24(1):119-127.
- doi: 10.5056/jnm17058
BACKGROUND/AIMS: Opioid-induced constipation (OIC) is the most common gastrointestinal (GI) side effect to opioid treatment. Opioid receptor antagonists against OIC have been introduced, but their efficacy has not been directly... -
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- Axial Movements and Length Changes of the Human Lower Esophageal Sphincter During Respiration and Distension-induced Secondary Peristalsis Using Functional Luminal Imaging Probe
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Liao D, Lottrup C, Fynne L, McMahon BP, Krogh K, Drewes AM, Zhao J, Gregersen
- KMID: 2413102
- J Neurogastroenterol Motil.
- 2018 Apr;24(2):255-267.
- doi: 10.5056/jnm17084
BACKGROUND/AIMS: Efficient transport through the esophago-gastric junction (EGJ) requires synchronized circular and longitudinal muscle contraction of the esophagus including relaxation of the lower esophageal sphincter (LES). However, there is a... -
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