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Modulation of protective immunity against herpes simplex virus via mucosal genetic co-transfer of DNA vaccine with beta2-adrenergic agonist

Kim SB, Han YW, Rahman MM, Kim SJ, Yoo DJ, Kang SH, Kim K, Eo SK

Cholera toxin, which has been frequently used as mucosal adjuvant, leads to an irreversible activation of adenylyl cyclase, thereby accumulating cAMP in target cells. Here, it was assumed that beta2-adrenergic...
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Immune responses in pigs and cattle vaccinated with half-volume foot-and-mouth disease vaccine

Park ME, You SH, Lee SY, Lee KN, Ko MK, Choi JH, Kim B, Lee JS, Park JH

With the current commercial foot-and-mouth disease vaccine, inoculating twice increases the formation of denatured meat due to granuloma or residual adjuvant at the injection site in pigs, resulting in economic...
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Efficiency of Matricaria chamomilla CH(12) and number of doses of rabies vaccine on the humoral immune response in cattle

de Souza Reis LS, Frazatti-Gallina NM, de Lima Paoli R, Giuffrida , Albas A, Oba E, Pardo PE

This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH(12)...
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Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri

Jeong SR, Kang SY, Lee SC, Song KJ, Im KI, Shin HJ

The nfa1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed...
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D60-sensitive tyrosine phosphorylation is involved in Fas-mediated phospholipase D activation

Kim JG, Shin IC, Lee KS, Han JS

  • KMID: 1457546
  • Exp Mol Med.
  • 2001 Dec;33(4):303-309.
Both Fas and PMA can activate phospholipase D via activation of protein kinase Cbeta in A20 cells. Phospholipase D activity was increased 4 fold in the presence of Fas and...
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Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection

Cho JH, Chung WS, Song KJ, Na BK, Kang SW, Song CY, Kim TS

Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against N. caninum infection was evaluated in vitro and in vivo. Two major immunodominant surface antigens (NcSAG1 and NcSRS2) and...
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