- Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury
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Uddin MJ, Dorotea D, Pak ES, Ha H
- KMID: 2500497
- Biomol Ther.
- 2020 May;28(3):213-221.
- doi: 10.4062/biomolther.2019.214
Acute kidney injury (AKI) is a common disease with a complex pathophysiology which significantly contributes to the development of chronic kidney disease and end stage kidney failure. Preventing AKI can... -
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- Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice
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Jiang S, Uddin MJ, Yu X, Piao L, Dorotea D, Oh GT, Ha H
- KMID: 2536142
- Diabetes Metab J.
- 2022 Nov;46(6):829-842.
- doi: 10.4093/dmj.2021.0274
Background: Non-alcoholic fatty liver disease (NAFLD) has been increasing in association with the epidemic of obesity and diabetes. Peroxisomes are single membrane-enclosed organelles that play a role in the metabolism... -
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- KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice
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Dorotea D, Lee S, Lee SJ, Lee G, Son JB, Choi HG, Ahn SM, Ha H
- KMID: 2510123
- Biomol Ther.
- 2021 Jan;29(1):41-51.
- doi: 10.4062/biomolther.2020.088
Src family kinases (SFKs), an important group of non-receptor tyrosine kinases, are suggested to be excessively activated during various types of tissue fibrosis. The present study investigated the effect of... -
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