- Efficacy of Asenapine in Drug-resistant Psychotic Patients with Dopamine Supersensitivity Psychosis: Two Cases
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Kanahara N, Kimura H, Kinoshita T, Iyo M, Takekita Y
- KMID: 2539664
- Clin Psychopharmacol Neurosci.
- 2023 Feb;21(1):197-201.
- doi: 10.9758/cpn.2023.21.1.197
Dopamine supersensitivity psychosis (DSP) is an unstable clinical condition observed in individuals with schizophrenia who have been treated with an antipsychotic medication at a high dosage and/or for a long... -
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- Rotigotine protects dopaminergic neurons through dopamine D2 receptor against 6-hydroxydopamine
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Lee Sj, Kim Mk, Won Ck
- KMID: 2510281
- J Biomed Transl Res.
- 2020 Dec;21(4):165-170.
- doi: 10.12729/jbtr.2020.21.4.165
Dopamine (DA) receptor (D1 and D2-like receptors) agonists are known to affect expression levels of DA receptors. Rotigotine, a DA D2-like receptor agonist, has been developed for treating Parkinson’s disease... -
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- Long-term Effects of Aripiprazole Treatment during Adolescence on Cognitive Function and Dopamine D2 Receptor Expression in Neurodevelopmentally Normal Rats
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Choi HJ, Im SJ, Park HR, Park S, Kim CE, Ryu S
- KMID: 2457403
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):400-408.
- doi: 10.9758/cpn.2019.17.3.400
OBJECTIVE: This study aimed to investigate the long-term effects of aripiprazole treatment during adolescence on behavior, cognitive function, and dopamine D2 receptor (D2R) expression in adult rats. METHODS: Adolescent male Sprague-Dawley... -
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- Central Nervous System Drug Evaluation Using Positron Emission Tomography
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Sekine M, Maeda J, Shimada H, Nogami T, Arakawa R, Takano H, Higuchi M, Ito H, Okubo Y, Suhara T
- KMID: 2171280
- Clin Psychopharmacol Neurosci.
- 2011 Apr;9(1):9-16.
In conventional pharmacological research in the field of mental disorders, pharmacological effect and dose have been estimated by ethological approach and in vitro data of affinity to the site of... -
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- Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats
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Jang HS, Kim JY, Kim SH, Lee MG
- KMID: 2071664
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):147-151.
- doi: 10.4196/kjpp.2009.13.3.147
Repeated psychostimulants induce electroencephalographic (EEG) changes, which reflect adaptation of the neural substrate related to dopaminergic pathways. To study the role of dopamine receptors in EEG changes, we examined the... -
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- The Relationship between Taq I A Dopamine D2 Receptor Polymorphism and Therapeutic Response to Antipsychotics in Schizophrenic Patients
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Kang CJ
- KMID: 2299952
- Korean J Biol Psychiatry.
- 2005 Nov;12(2):107-113.
PURPOSE: In an attempt to predict the interpersonal differences of therapeutic response to antipsychotic drugs on pharmaco-genetic bases, this study was designed to investigate the relationship between the therapeutic response... -
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- Effects of Newer Antipsychotic Drugs on Apomorphine-Induced Climbing Behavior in Mice
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Jeong SH, Kim JY, Kim E, Chung IW
- KMID: 2286787
- Korean J Psychopharmacol.
- 2005 Nov;16(6):455-461.
OBJECTIVE: Chlorpromazine equivalence was used to chart relative potencies of typical antipsychotic agents and it has been known to be in a linear relationship with dopamine D2 receptor affinity. After... -
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- Increased expression of dopamine receptors and transporter and hypomethylation of dopamine transporter gene in uterine leiomyoma
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Kim JH, Kim MJ, Choo YA, Choi YS, Lee TS, Kim HT
- KMID: 2128061
- Korean J Obstet Gynecol.
- 2005 Mar;48(3):628-637.
OBJECTIVE: Dopamine plays a key role in the proliferation regulation of the smooth muscle cells. The purpose of this study was to observe the degree of expression of dopamine D1... -
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- Dopamine D2 Receptor Gene Polymorphism in Cigarette Smoking
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Lee HS, Song SM, Lee HJ
- KMID: 2340818
- J Korean Neuropsychiatr Assoc.
- 2003 Mar;42(2):202-207.
OBJECTIVE: This study was to examine the effects of DRD2 TaqI A polymorphism on the smoking in Koreans. Also this study examined molecular heterosis and gender difference in the genetic... -
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- The Dopamine D2 Receptor Locus as a Modifying Gene in Korean Schizophrenia, Alcoholism and Drug Addiction
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Jung HM, Lee HS, Chang DW, Lee MS
- KMID: 2202984
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):225-233.
The authors attempted to examine the allelic association between the A1 allele of Dopamine D2 receptor and schizophrenia, alcoholism, drug addiction in Koreans. Schizophrenic patients(n=31), alcoholism(n=65), drug addiction(n=18) and controls(n=52)... -
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- Association between the Alleles of the Dopamine D, Receptor and Schizophrenia
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Kim JI, Lee MS, Kwak DI
- KMID: 2202983
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):218-224.
The results regarding an association between the polymorphism sites in the dopamine D1 receptor gene and schizophrenia compelled us to study the distribution of the polymorphism in Korean schizophrenia and... -
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- N-( 4-[ 18F ] Fluoromethylbenzyl ) spiperone: A Selective Radiotracer for In Vivo Studies of Dopamine D2 Receptors
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Kim SE, Choe YS, Chi DY, Lee KH, Choi Y, Kim BT
- KMID: 2078655
- Korean J Nucl Med.
- 1997 Nov;31(4):421-426.
We evaluated the in vivo kinetics, distribution, and pharmacology of N-(4-[F] fluorornethylbenzyl)spiperone ([F]FMBS), a newly developed derivative of spiperone, as a potentially more selective #radiotrar.er for the dopamine (DA) Dz... -
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- Allelic Association of the Dopamine D2Receptor in Korean Alcoholics
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Lee KJ, Lee MS, Kwak DI
- KMID: 1944943
- J Korean Soc Biol Psychiatry.
- 1997 Jun;4(1):43-47.
The author attempted to allelic association between the a1 allele of Dopamine D2 receptor and alcoholism in Korean. The allelic disribution of Taq I polymorphism of the D2 dopamine receptor... -
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