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13-week subchronic toxicity study of a novel ginsenoside composition from ginseng leaves in rats

Shin WH, Ri Y, Do SG, Lee YC, Park SJ

UG0712 is a new ginsenoside extract processed from ginseng leaves. A subchronic toxicity study of UG0712 was conducted in male and female SD rats. Rats were treated with UG0712 at...
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Evaluation of the genotoxicity of ginseng leaf extract UG0712

Kim JY, Ri Y, Do SG, Lee YC, Park SJ

Although ginseng (genus Panax) leaf extract contains high concentrations of bioactive constituents, its effects have been reported in few preclinical studies, and information regarding its toxicity is not sufficient to...
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Silk fibroin hydrolysate exerts an anti-diabetic effect by increasing pancreatic beta cell mass in C57BL/KsJ-db/db mice

Do SG, Park JH, Nam H, Kim JB, Lee JY, Oh YS, Suh JG

  • KMID: 2391991
  • J Vet Sci.
  • 2012 Dec;13(4):339-344.
Components of silk including silk fibroin have long been used as anti-diabetic remedies in oriental medicine. However, detailed mechanisms underlying these anti-diabetic effects remain unclear. In this study, we examined...
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A standardized bamboo leaf extract inhibits monocyte adhesion to endothelial cells by modulating vascular cell adhesion protein-1

Choi S, Park MS, Lee YR, Lee YC, Kim TW, Do SG, Kim DS, Jeon BH

  • KMID: 2313643
  • Nutr Res Pract.
  • 2013 Feb;7(1):9-14.
Bamboo leaves (Phyllostachys pubescens Mazel ex J. Houz (Poacea)) have a long history of food and medical applications in Asia, including Japan and Korea. They have been used as a...
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Arginine vasopressin (AVP) expressional changes in the hypothalamic paraventricular and supraoptic nuclei of stroke-prone spontaneously hypertensive rats

Yi SS, Kim HJ, Do SG, Lee YB, Ahn HJ, Hwang IK, Yoon YS

Arginine vasopressin (AVP) is a neuropeptide with vasoconstrictive, antidiuretic, cardiovascular regulative and hepatic glycogenolysis effects, that also affects other behaviors including modulating learning. A number of studies on AVP regulation...
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Dietary Aloe QDM Complex Reduces Obesity-Induced Insulin Resistance and Adipogenesis in Obese Mice Fed a High-Fat Diet

Shin S, Kim S, Oh HE, Kong H, Shin E, Do SG, Jo TH, Park YI, Lee CK, Kim K

Obesity-induced disorders contribute to the development of metabolic diseases such as insulin resistance, fatty liver diseases, and type 2 diabetes (T2D). In this study, we evaluated whether the Aloe QDM...
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The Synergy Effect of Weight-Bearing Circuit Training and Aloe QDM Complex on Obese Middle Aged Women: a Randomized Double-Blind Controlled Trial

Choi MJ, Kim YA, Shin E, Do SG, Song W

BACKGROUND: Obesity is a major health problem and leads to metabolic diseases such as type 2 diabetes, insulin resistance and hyperlipidemia. Recently, it was reported that aloe QDM complex, composed...
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Dietary Aloe Reduces Adipogenesis via the Activation of AMPK and Suppresses Obesity-related Inflammation in Obese Mice

Shin E, Shin S, Kong H, Lee S, Do SG, Jo TH, Park YI, Lee CK, Hwang IK, Kim K

BACKGROUND: Metabolic disorders, including type II diabetes and obesity, present major health risks in industrialized countries. AMP-activated protein kinase (AMPK) has become the focus of a great deal of attention...
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Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis

Zhong X, Surh YJ, Do SG, Shin E, Shim KS, Lee CK, Na HK

BACKGROUND: Baicalein is a bioactive flavone that is originally extracted from the root of Scutellaria baicalensis Georgi. This plant has long served as Chinese herbal medicine in the management of...
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