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Prevalence and molecular analysis of glucose-6-phosphate dehydrogenase deficiency in Chin State, Myanmar

Aung JM, Moon Z, VanBik D, Dinzouna-Boutamba SD, Lee S, Ring Z, Chung DI, Hong Y, Goo YK

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is caused by X-linked recessive disorderliness. It induces severe anemia when a patient with G6PD deficiency is exposed to oxidative stress that occurs with administration of...
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Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates from central Myanmar

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by the polymorphic var multigene family, is a highly polymorphic antigen that plays a crucial role in the pathology of malaria. The...
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Population genetic analysis of Plasmodium vivax vir genes in Pakistan

Dinzouna-Boutamba SD, Moon Z, Lee S, Afridi SG, Lê HG, Hong Y, Na BK, Goo YK

Plasmodium vivax variant interspersed repeats (vir) refer to the key protein used for escaping the host immune system. Knowledge in the genetic variation of vir genes can be used for...
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Distribution of Antibodies Specific to the 19-kDa and 33-kDa Fragments of Plasmodium vivax Merozoite Surface Protein 1 in Two Pathogenic Strains Infecting Korean Vivax Malaria Patients

Dinzouna-Boutamba SD, Lee S, Son UH, Song SM, Yun HS, Joo SY, Kwak D, Rhee MH, Chung DI, Hong Y, Goo YK

Objectives Plasmodium vivax merozoite surface protein 1 (PvMSP1) is the most intensively studied malaria vaccine candidate. Although high antibody response-inducing two C-terminal fragments of PvMSP1 (PvMSP1-19 and PvMSP1-42) are currently being...
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Diversity of vir Genes in Plasmodium vivax from Endemic Regions in the Republic of Korea: an Initial Evaluation

Son UH, Dinzouna-Boutamba SD, Lee S, Yun HS, Kim JY, Joo SY, Jeong S, Rhee MH, Hong Y, Chung DI, Kwak D, Goo YK

Variant surface antigens (VSAs) encoded by pir families are considered to be the key proteins used by many Plasmodium spp. to escape the host immune system by antigenic variation. This...
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