- Efonidipine, Another Beauty Relieving the Pressure
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Shin J
- KMID: 2225014
- Korean Circ J.
- 2012 Apr;42(4):229-230.
- doi: 10.4070/kcj.2012.42.4.229
No abstract available. -
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- Two Cases of Severe Hyperglycemia after Overdose of Amlodipine
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Na HS, Ann HS, Ha TH, Gil HW, Yang JO, Lee EY, Hong SY
- KMID: 2307250
- Korean J Nephrol.
- 2005 Sep;24(5):856-859.
Amlodipine, a calcium channel blocker (CCB) belonging to the group of dihydropyridines, is characterized by a slower onset of action (6-8h), a longer duration of action (24-72h), a greater vascular,... -
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- Antiplatelet Effect of Clopidogrel Can Be Reduced by Calcium-Channel Blockers
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Seo KD, Kim YD, Yoon YW, Kim JY, Lee KY
- KMID: 2068678
- Yonsei Med J.
- 2014 May;55(3):683-688.
- doi: 10.3349/ymj.2014.55.3.683
PURPOSE: Clopidogrel is metabolized by the hepatic cytochrome P450 (CYP) system into its active thiol metabolite. CYP3A4 is involved in the metabolism of both clopidogrel and dihydropyridine calcium channel blockers... -
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- Effect of an L- and T-Type Calcium Channel Blocker on 24-Hour Systolic Blood Pressure and Heart Rate in Hypertensive Patients
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Komukai M, Tsutsumi T, Ebado M, Takeyama Y
- KMID: 2225015
- Korean Circ J.
- 2012 Apr;42(4):231-238.
- doi: 10.4070/kcj.2012.42.4.231
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the effects of an L- and T-type calcium channel blocker (CCB) on 24-hour systolic blood pressure (24-hour SBP) and... -
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- Single center, Randomized, Single-blind, Parallel-group, Phase IV Clinical Trial for the Comparison of Efficacy and Safety between S-(-)-Amlodipine Nicotinate and Lercanidipine HCl in patients with hypertension
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Youn JS, Ahn YS, Hwang YJ, Jung HM, Kim WJ, Lee MG, Kim SH, Kim JY, Cho JH
- KMID: 2330953
- J Korean Soc Hypertens.
- 2010 Mar;16(1):18-30.
BACKGROUND: RS amlodipine, a third generation dihydropyridine calcium channel blocker is a widely used antihypertensive medicine. It is an mixture of S-amlodipine and R-amlodipine isomers. S-amlodipine is known to have... -
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- Intracisternal Administration of Voltage Dependent Calcium Channel Blockers Attenuates Orofacial Inflammatory Nociceptive Behavior in Rats
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Won KA, Park SH, Kim BK, Baek KS, Yoon DH, Ahn DK
- KMID: 2170724
- Int J Oral Biol.
- 2011 Jun;36(2):43-50.
Voltage dependent calcium channel (VDCC), one of the most important regulator of Ca2+ concentration in neuron, play an essential role in the central processing of nociceptive information. The present study... -
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- Comparison of Pharmacokinetic Characteristics and the Safety between Amlodipine Maleate Tablet 5 mg and Amlodipine Besylate Tablet 5 mg
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Choi HY, Kim JW, Lim HS, Cho SH, Ghim JL, Choe S, Jung JA, Lim J, Bae KS
- KMID: 2334517
- J Korean Soc Clin Pharmacol Ther.
- 2012 Jun;20(1):42-50.
BACKGROUND: Amlodipine is a third-generation dihydropyridine calcium channel blocker for treating hypertension. Though marketed primarily as a besylate salt, there have been some efforts to find other comparable salts. Among... -
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- Effect of Efonidipine on Proteinuria in Patients with Chronic Kidney Disease Receiving RAS Blockade
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Wi JK, Jeong KW, Lee TW, Lee SH, Moon JY, Cha DR, Ha SK, Kim SB, Kwak IS, Ihm CG
- KMID: 1855492
- Korean J Nephrol.
- 2010 May;29(3):322-328.
PURPOSE: Efonidipine, which inhibits both T- and L-type calcium channels, has been shown to be effective in reducing proteinuria and preserve renal function. This study was conducted to compare the... -
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- Beneficial Effect of Efonidipine, an L- and T-Type Dual Calcium Channel Blocker, on Heart Rate and Blood Pressure in Patients With Mild-to-Moderate Essential Hypertension
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Oh IY, Seo MK, Lee HY, Kim SG, Kim KS, Kim WH, Hyon MS, Han KR, Lim SJ, Kim CH
- KMID: 1826140
- Korean Circ J.
- 2010 Oct;40(10):514-519.
- doi: 10.4070/kcj.2010.40.10.514
BACKGROUND AND OBJECTIVES: Efonidipine hydrochloride, an L- and T-type dual calcium channel blocker, is suggested to have a heart rate (HR)-slowing action in addition to a blood pressure (BP)-lowering effect.... -
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- Influence of Ketamine on Catecholamine Secretion in the Perfused Rat Adrenal Medulla
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Ko YY, Jeong YH, Lim DY
- KMID: 2285350
- Korean J Physiol Pharmacol.
- 2008 Jun;12(3):101-109.
- doi: 10.4196/kjpp.2008.12.3.101
The aim of the present study was to examine the effects of ketamine, a dissociative anesthetics, on secretion of catecholamines (CA) secretion evoked by cholinergic stimulation from the perfused model... -
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- Provinol Inhibits Catecholamine Secretion from the Rat Adrenal Medulla
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Lee JH, Seo YS, Lim DY
- KMID: 2071676
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):229-239.
- doi: 10.4196/kjpp.2009.13.3.229
The aim of the present study was to examine the effect of provinol, which is a mixture of polyphenolic compounds from red wine, on the secretion of catecholamines (CA) from... -
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- Polyphenols of Rubus coreanum Inhibit Catecholamine Secretion from the Perfused Adrenal Medulla of SHRs
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Yu BS, Na DM, Kang MY, Lim DY
- KMID: 2285390
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):517-526.
- doi: 10.4196/kjpp.2009.13.6.517
The present study was attempted to investigate whether polyphenolic compounds isolated from wine, which is brewed from Rubus coreanum Miquel (PCRC), may affect the release of catecholamines (CA) from the... -
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- Resveratrol Inhibits Nicotinic Stimulation-Evoked Catecholamine Release from the Adrenal Medulla
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Woo SC, Na GM, Lim DY
- KMID: 1838353
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):155-164.
- doi: 10.4196/kjpp.2008.12.4.155
Resveratrol has been known to possess various potent cardiovascular effects in animal, but there is little information on its functional effect on the secretion of catecholamines (CA) from the perfused... -
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- Effect of Lacidipine on Blood Pressure and Endothelial Function in Mild-to-Moderate Essential Hypertension Patients With Diabetes in Korea
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Kim DH, Oh IY, Lee HY, Kim YJ, Kim HS, Kim CH, Oh BH, Kim KS, Kim DI, Kim YD, Ryu KH, Park SH, Baek SH, Shin DG, Shim WJ, Ahn TH, Oh SK, Lee SH, Lee SY, Jeong MH, Chung WS, Jeong JY, Choi SY, Choi SW, Hyon MS
- KMID: 2225161
- Korean Circ J.
- 2010 Dec;40(12):632-638.
- doi: 10.4070/kcj.2010.40.12.632
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the efficacy of lacidipine in reducing blood pressure (BP) and to determine its effect on endothelial function in mild-to-moderate... -
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