- A Case of Areolar Sebaceous Hyperplasia Treated with Dichloroacetic Acid
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Yu M, Han TY, Lee H, Son SJ
- KMID: 2247540
- Korean J Dermatol.
- 2011 Nov;49(11):1046-1048.
Sebaceous hyperplasia is a common disease in middle-aged adults. The lesions usually present as solitary or multiple yellowish tiny papules on the face. The areola, vulva and penis are rarely... -
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- The Effectiveness and Safety of Local Bichloroacetic Acid in the Treatment of Xanthelasma Palpebrarum
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Jeong SY, Shin JB, Seo SH, Son SW, Kim IH
- KMID: 1931115
- Korean J Dermatol.
- 2007 Apr;45(4):349-353.
BACKGROUND: Xanthelasma palpebrarum is the most common type of xanthoma. Due to its delicate location near the eye, treatment of xanthelasma palpebrarum is rather difficult. The treatment includes surgical excision,... -
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- Clinical Application of BCA Focal Treatment for Various Skin Diseases: Surgical Gems II
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Kim YJ, Hwang ES, Yu DS, Kim IH
- KMID: 1977857
- Korean J Dermatol.
- 2003 Dec;41(12):1633-1637.
Bichloroacetic acid(BCA), one of the chloroacetic acids, is an effective tissue cauterant when used in high concentration. In dermatologic surgery, BCA, in the form of 100% solution, has been used... -
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- Inhibition of Sarcoplasmic Reticulum Ca2+ Uptake by Pyruvate and Fatty Acid in H9c2 Cardiomyocytes: Implications for Diabetic Cardiomyopathy
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Lee EH, Lee HK, Kim HW, Kim YH
- KMID: 1600069
- Korean J Physiol Pharmacol.
- 2005 Aug;9(4):195-201.
High extracellular glucose concentration was reported to suppress intracellular Ca2+ clearing through altered sarcoplasmic reticulum (SR) function. In the present study, we attempted to elucidate the effects of pyruvate and... -
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- Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas
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Jha MK, Suk K
- KMID: 2048476
- Brain Tumor Res Treat.
- 2013 Oct;1(2):57-63.
- doi: 10.14791/btrt.2013.1.2.57
Metabolic aberrations in the form of altered flux through key metabolic pathways are the major hallmarks of several life-threatening malignancies including malignant gliomas. These adaptations play an important role in... -
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- Effects of Insulin, 2-Deoxyglucose and Dichloroacetate on Acute Focal Cerebral Ischemia in Rats
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Chung HS, Park YK, Lee HG, Lee KC, Chu JW
- KMID: 1688190
- J Korean Neurosurg Soc.
- 1991 May;20(5):336-344.
Hyperglycemia has been reported to worsen the tolerance of the brain to ischemia, and it has therefore been recommended that patient undergoing neurosurgical procedures not receive glucose-containing solutions. Since ischemic... -
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- Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate
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Constantin-Teodosiu D
- KMID: 1965976
- Diabetes Metab J.
- 2013 Oct;37(5):301-314.
- doi: 10.4093/dmj.2013.37.5.301
Since the mitochondrial pyruvate dehydrogenase complex (PDC) controls the rate of carbohydrate oxidation, impairment of PDC activity mediated by high-fat intake has been advocated as a causative factor for the... -
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- Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme
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Han JE, Lim PW, Na CM, Choi YS, Lee JY, Kim Y, Park HW, Moon HE, Heo MS, Park HR, Kim DG, Paek SH
- KMID: 2398434
- Exp Neurobiol.
- 2017 Oct;26(5):295-306.
- doi: 10.5607/en.2017.26.5.295
Glioblastoma multiforme (GBM) is the most common and aggressive form of brain tumors. GBMs, like other tumors, rely relatively less on mitochondrial oxidative phosphorylation (OXPHOS) and utilize more aerobic glycolysis,... -
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