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The Effects of Excitation-Contraction Uncouplers on the Dynamics of Ventricular Fibrillation in Isolated Swine Right Ventricles

Lee MH, Karagueuzian HS, Chen PS

BACKGROUND: Whether or not the excitation-contraction (EC) uncoupler, diacetyl monoxime (DAM) and cytochalacin D (Cyto D) alter the ventricular fibrillation activation patterns is unclear. METHODS: We recorded single cell action...
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Synthesis of d- and l-Form of 99mTc-HMPAO, and Comparison of Brain Uptake

Kang CS, Chang YS, Jeong JM, Lee DS, Chung JK, Lee KC, Lee MC

  • KMID: 2078736
  • Korean J Nucl Med.
  • 2001 Feb;35(1):69-74.
PURPOSE: 99mTc-HMPAO is a radiopharmaceutical for imaging cerebral blood flow. HMPAO (RR, SS)-4,8- diaza-3,6,6,9-tetramethylundecan-2,10- dione bisoxime) has three stereoismers such as, meso-, d-, and l-HMPAO. Techentium complexes of meso-HMPAO and...
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Effect of pralidoxime on coronary perfusion pressure during cardiopulmonary resuscitation in a pig model

Jung YH, Ryu DH, Jeung KW, Na JY, Lee DH, Lee BK, Heo T, Min YI

OBJECTIVE: Pralidoxime is widely used for the treatment of organophosphate poisoning. Multiple studies have reported its vasoconstrictive property, which may facilitate the restoration of spontaneous circulation (ROSC) after cardiac arrest...
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Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases

Park MH, Igarashi K

  • KMID: 2170679
  • Biomol Ther.
  • 2013 Jan;21(1):1-9.
Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are essential for eukaryotic cell growth. These polycations interact with negatively charged molecules such as DNA, RNA, acidic proteins...
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