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The prevalence of diabetic peripheral neuropathy in youth with diabetes mellitus

Sophausvaporn P, Boonhong J, Sahakitrungruang T

Purpose: Diabetic neuropathy (DN) is a serious complication in diabetes mellitus. We aimed to determine the prevalence of DN in pediatric-onset diabetes in a tertiary care center and to assess...
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Diabetic Neuropathy and Risk of Cardiovascular Disease

Yun JS

Neuropathy is a common complication of diabetes that can appear in the early stages of diabetes or even in the prediabetes stage. The relationship between autonomic neuropathy and cardiovascular disease...
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Management of Intractable Painful Diabetic Peripheral Neuropathy: The Perspective of a Pain Specialist

Moon JY

Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. The most common diabetic neuropathy (DN) is distal symmetric polyneuropathy, with characteristic glove-...
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Quantification of Nerve Viscosity Using Shear Wave Dispersion Imaging in Diabetic Rats: A Novel Technique for Evaluating Diabetic Neuropathy

Liu F, Li D, Xin Y, Liu F, Li W, Zhu J

Objective: Viscoelasticity is an essential feature of nerves, although little is known about their viscous properties. The discovery of shear wave dispersion (SWD) imaging has presented a new approach for...
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Validity of the diagnosis of diabetic microvascular complications in Korean national health insurance claim data

Kim HJ, Park MS, Kim JE, Song TJ

Background: There is inadequate information on the validation of diabetic microvascular complications in the Korean National Health Insurance Service data set. We aimed to validate the diagnostic algorithms regarding the...
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Effect of Rutin on Diabetic Auditory Neuropathy in an Experimental Rat Model

Doostkam A, Mirkhani H, Iravani K, Karbalay-Doust S, Zarei K

Objectives. Diabetic auditory neuropathy is a common complication of diabetes mellitus that has a major impact on patients’ quality of life. In this study, we assessed the efficacy of rutin...
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Diabetic Peripheral Neuropathy as a Risk Factor for Sarcopenia

Oh TJ, Song Y, Moon JH, Choi SH, Jang HC

BACKGROUND: Diabetic peripheral neuropathy (DPN) is prevalent in patients with type 2 diabetes, and its prevalence increases with age. A previous study demonstrated the association between DPN and muscle dysfunction;...
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Association between Body Fat and Diabetic Peripheral Neuropathy in Middle-Aged Adults with Type 2 Diabetes Mellitus: A Preliminary Report

Oh TJ, Lee JE, Choi SH, Jang HC

BACKGROUND: Previous epidemiologic studies showed that obesity increased the risk of diabetic peripheral neuropathy (DPN). However, there is very limited data about the impact of body fat measured by body...
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Effects of Repetitive High Frequency Motor Cortex Transcranial Magnetic Stimulation and Cortical Disinhibition in Diabetic Patients with Neuropathic Pain: A Case Control Study

Han Y, Lee CH, Min KW, Han KA, Choi HS, Kang YJ

OBJECTIVE: To investigate the cortical disinhibition in diabetic patients with neuropathic pain and without pain. In addition, we assessed the cortical disinhibition and pain relief after repetitive transcranial magnetic stimulation...
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7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress

Cho SJ, Kang KA, Piao MJ, Ryu YS, Fernando P, Zhen AX, Hyun YJ, Ahn MJ, Kang HK, Hyun JW

Oxidative stress is considered a major contributor in the pathogenesis of diabetic neuropathy and in diabetes complications, such as nephropathy and cardiovascular diseases. Diabetic neuropathy, which is the most frequent...
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Diagnosis and Management of Diabetic Autonomic Neuropathy

Kim CH

Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes, although it is often overlooked. Abnormal autonomic function tests are often found in peoples with diabetic peripheral neuropathy....
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Clinical Importance of Diabetic Neuropathy

Park TS

Diabetic neuropathy is a complex and common disorder with multiple etiologies and affects about 43.1% of the Korean diabetes population. Good glycemic control slows progression of diabetic neuropathy in subjects...
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Assessment of Diabetic Peripheral Neuropathy Using Current Perception Threshold

Kim KT, Lee S

The aim of this study was to compare the current perception threshold (CPT) with a nerve conduction study (NCS) to evaluate the usefulness of CPT in the diagnosis of diabetic...
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Prevalence and Risk Factors of Gastroesophageal Reflux Disease in Patients with Type 2 Diabetes Mellitus

Ha JO, Lee TH, Lee CW, Park JY, Choi SH, Park HS, Lee JS, Lee SH, Seo EH, Kim YH, Kang YW

BACKGROUND: Gastrointestinal symptoms are common in patients with type 2 diabetes mellitus (T2DM). The prevalence of gastroesophageal reflux disease (GERD) in Korea appears to be increasing. Some studies have shown...
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Diabetic peripheral neuropathy class prediction by multicategory support vector machine model: a cross-sectional study

Kazemi M, Moghimbeigi A, Kiani J, Mahjub H, Faradmal J

OBJECTIVES: Diabetes is increasing in worldwide prevalence, toward epidemic levels. Diabetic neuropathy, one of the most common complications of diabetes mellitus, is a serious condition that can lead to amputation....
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Management of Diabetic Peripheral Neuropathy

Kang MS, Kim CH

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. The prevalence of neuropathic pain is estimated to occur in about 30-50% of all diabetic patients. Clinical symptoms vary...
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Diabetic Foot Education and a Diabetic Foot Screening Tool

Lee JH

People with diabetes mellitus develop lower-limb complications such as diabetic neuropathy, peripheral vascular disease, foot ulcers, and lower-leg amputations. Widespread failure to carry out diabetic foot screening can lead to...
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Up-Regulation of the Receptor for Advanced Glycation End Products in the Skin Biopsy Specimens of Patients with Severe Diabetic Neuropathy

Park SY, Kim YA, Hong YH, Moon MK, Koo BK, Kim TW

BACKGROUND AND PURPOSE: The receptor for advanced glycation end products (RAGE) may contribute to the development of diabetic neuropathy. To assess its relevance in humans, this study examined the expression...
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Effects of Nefopam on Streptozotocin-Induced Diabetic Neuropathic Pain in Rats

Nam JS, Cheong YS, Karm MH, Ahn HS, Sim JH, Kim JS, Choi SS, Leem JG

BACKGROUND: Nefopam is a centrally acting non-opioid analgesic agent. Its analgesic properties may be related to the inhibitions of monoamine reuptake and the N-methyl-D-aspartate (NMDA) receptor. The antinociceptive effect of...
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Assessment of Diabetic Polyneuropathy and Autonomic Neuropathy Using Current Perception Threshold in Korean Patients with Diabetes Mellitus

Koo BK, Ohn JH, Kwak SH, Moon MK

BACKGROUND: The current perception threshold (CPT) could be quantified by stimulating Abeta and C fibers at 2,000 and 5 Hz, respectively. C fibers play a role in the autonomic nervous...
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