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Ginseng Total Saponin Improves Podocyte Hyperpermeability Induced by High Glucose and Advanced Glycosylation Endproducts

Ha TS, Choi JY, Park HY, Lee JS

Early diabetic nephropathy is characterized by glomerular hyperpermeability as a result of impaired glomerular filtration structure caused by hyperglycemia, glycated proteins or irreversible advanced glycosylation endproducts (AGE). To investigate the...
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Role of nitric oxide in the pathogenesis of diabetic nephropathy in streptozotocin-induced diabetic rats

Choi KC, Lee SC, Kim SW, Kim NH, Lee JU, Kang YJ

  • KMID: 759082
  • Korean J Intern Med.
  • 1999 Jan;14(1):32-41.
OBJECTIVES: Several reports suggest that enhanced generation or actions of nitric oxide (NO) have been implicated in the pathogenesis of glomerular hyperfiltration and hyperperfusion that occurs in early...
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The Impact of Diabetes Mellitus on Vascular Biomarkers in Patients with End-Stage Renal Disease

Moon J, Lee CJ, Lee SH, Kang SM, Choi D, Yoo TH, Park S

PURPOSE: Diabetes mellitus (DM) is the most common cause of end-stage renal disease (ESRD) and an important risk factor for cardiovascular (CV) disease. We investigated the impact of DM on...
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