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Effect of Phosphodiesterase Inhibitor on Diabetic Nephropathy

Kang SW

No abstract available.
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The renoprotective effects of pentoxifylline: beyond its role in diabetic nephropathy

Kapoor S

No abstract available.
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The Role of Free Radical in the Pathogenesis of Impotence in Streptozotocin-Induced Diabetic Rats

Ryu JK, Kim DJ, Lee T, Kang YS, Yoon SM, Suh JK

Diabetes is the most common cause of erectile dysfunction (ED). Oxidative stress has been suggested to be a contributory factor in vascular complications of diabetes in various organs. In the...
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Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms

Xi S, Zhou G, Zhang X, Zhang W, Cai L, Zhao C

Total aralosides of Aralia elata (Miq) Seem (TASAES) from Chinese traditional herb Longya Aralia chinensis L was found to improve cardiac function. The present study was to determine the protective...
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Effective glycemic control achieved by transplanting non-viral cationic liposome-mediated VEGF-transfected islets in streptozotocin-induced diabetic mice

Chae HY, Lee BW, Oh SH, Ahn YR, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 1116196
  • Exp Mol Med.
  • 2005 Dec;37(6):513-523.
Hypoxic damage is one of the major causes of islet graft failure and VEGF is known to play a crucial role in revascularization. To address the effectiveness of a cationic...
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Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney

Sun HK, Lee YM, Han KH, Kim HS, Ahn SH, Han SY

BACKGROUND/AIMS: Renal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve...
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