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Effects of Vacuuming Mattresses on Allergic Rhinitis Symptoms in Children

Jeon YH, Lee YJ, Sohn MH, Lee HR

PURPOSE: To evaluate the effects of daily vacuuming of mattresses on the concentration of house dust mite (HDM) allergens and on allergic rhinitis (AR) symptoms in children sensitized to HDM. METHODS:...
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Usefulness of Allerkin House Dust Mite Extract for Nasal Provocation Testing

Kim KS, Jang TY, Kim YH

OBJECTIVES: We evaluated the clinical usefulness of Allerkin (Lofarma) for nasal provocation testing (NPT) in patients with rhinitis symptoms, by examining changes in nasal symptoms and acoustic parameters after exposure...
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House Dust Mite Sensitization Is Inversely Associated with Plasma 25-Hydroxyvitamin D3 Levels in Patients with Severe Atopic Dermatitis

Jang YH, Sim HB, Moon SY, Lee WJ, Lee SJ, Jin M, Kim SH, Kim DW

BACKGROUND: The relationship between atopic dermatitis (AD) and low vitamin D levels has been studied. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role...
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Systemic Reactions to Dust Mite Subcutaneous Immunotherapy: A 3-Year Follow-up Study

Dong X, Huang N, Li W, Hu L, Wang X, Wang Y, Xiang N, Liu G, Zhu R

PURPOSE: The incidence of allergen specific immunotherapy-related systemic reactions (SRs) varies among different studies, and many factors are likely to contribute to SRs. This study aims to investigate the incidence,...
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Comparison of IgE-binding components between 2 house dust mites in adult allergic patients

Jin HJ, Yoon MG, Nam YH, Ahn JH, Park HS, Chung JH

PURPOSE: This study investigated the differences in the profile of IgE-binding components between Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farina (Df) in respiratory allergic patients sensitized to Dp/Df. METHODS: Eighteen patients with...
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Der p 1, Der p 2 and Der p 10 IgE Reactivities in Allergic Rhinitis Patients in Korea

Choi KY, Kim DY

BACKGROUND AND OBJECTIVES: To evaluate IgE reactivity profiles to Der p 1, Der p 2, and Der p 10 in house dust mite (HDM) allergic rhinitis (AR) patients in Korea....
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Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter

Liao EC, Hsieh CW, Chang CY, Yu SJ, Sheu ML, Wu SM, Tsai JJ

PURPOSE: Myeloid differentiation-2 (MD-2) has been associated with endotoxin and inflammatory disorders because it can recognize lipopolysaccharide (LPS) binding and attenuate Toll-like receptor 4 (TLR4)-mediated signaling. However, its role in...
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Immunoglobulin E to allergen components of house dust mite in Korean children with allergic disease

Kim HS, Kang SH, Won S, Lee EK, Chun YH, Yoon JS, Kim HH, Kim JT

BACKGROUND: House dust mites (HDMs) are important sources of indoor allergens. Seventeen components have been identified from Dermatophagoides pteronyssinus (Der p). OBJECTIVE: Our aim was to define the prevalence of specific...
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Association of Single Nucleotide Polymorphisms in the MD-2 Gene Promoter Region With Der p 2 Allergy

Liao EC, Chang CY, Wu CC, Wang GJ, Tsai JJ

PURPOSE: Sensitization to house dust mite (Dermatophagoides pteronyssinus) is a considerable risk factor for the progression of allergic disease. The group 2 allergen from Dermatophagoides pteronyssinus, Der p 2, is...
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Comparison of short-term effects between subcutaneous and sublingual immunotherapies in children with house dust mite-sensitized allergic rhinitis and asthma

Lee E, Kim MJ, Yang SI, Yu J, Hong SJ

PURPOSE: There have been several studies on comparisons of efficacy between subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) in children with house dust mite (HDM)-sensitized allergic rhinitis (AR), without consistent...
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Sensitization to House Dust Mites: Association with Airway Hyperresponsiveness in Mite-Sensitive Young Adults with Asthma

  • KMID: 2299469
  • Korean J Asthma Allergy Clin Immunol.
  • 2012 Sep;32(3):183-189.
BACKGROUND: The aim of this study was to evaluate the correlation between sensitization to mite and airway hyperresponsiveness in mite-sensitive young adults with asthma. METHODS: This study included 72 young male...
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Sensitization to Aeroallergens in Korean Children: A Population-based Study in 2010

Kim J, Hahm MI, Lee SY, Kim WK, Chae Y, Park YM, Han MY, Lee KJ, Kwon HJ, Jung JA, Kim SY, Ahn K

We performed this study to assess the prevalence of sensitization to aeroallergens and to analyze the difference between prevalence rates according to children's ages and residential areas. In this nationwide...
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Association of house dust mite-specific IgE with asthma control, medications and household pets

Albano PM, Ramos JD

BACKGROUND: Evidence is conflicting regarding the effectiveness of creating a low-allergen environment or reducing allergen exposure to control asthma exacerbations. OBJECTIVE: This study determined the association of house dust mite (HDM)-specific...
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Enzymatic Activities of Allergen Extracts from Three Species of Dust Mites and Cockroaches Commonly Found in Korean Home

Jeong KY, Kim C, Yong TS

Allergen extracts from dust mites and cockroaches commonly found in Korean homes were used to evaluate their enzymatic activity as they are believed to influence allergenicity. Allergen extracts were prepared...
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Association Between Serum IgE Levels and the CTLA4 +49A/G and FCER1B -654C/T Polymorphisms in Korean Children With Asthma

Oh KY, Kang MJ, Choi WA, Kwon JW, Kim BJ, Yu J, Hong SJ

PURPOSE: T cells play a central role in cell-mediated immunity, atopic disease, and asthma. The balance of CD28/cytotoxic T-lymphocyte antigen 4 (CTLA4)-derived signal transduction plays an important role in the...
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Risk Factors for Adenoid Hypertrophy in Children with Allergic Rhinitis

  • KMID: 2299526
  • Korean J Asthma Allergy Clin Immunol.
  • 2010 Dec;30(4):299-306.
BACKGROUND: Many children who have allergic rhinitis (AR) have adenoid hypertrophy (AH) which can cause significant morbidity. OBJECTIVE: To know the risk factors for AH in children with AR. METHOD: 208 children...
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House Dust Mite Allergens in Domestic Homes in Cheonan, Korea

Nam HS, Siebers R, Lee SH, Park JS, Kim YB, Choi YJ, Lee SH, Crane J

House dust mites produce inhalant allergens of importance to allergic patients. We measured the major group 1 allergens, Der p 1 and Der f 1, from the house dust mites...
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Validity of MAST-CLA for diagnosis of arthropod allergy using receiver operating characteristic (ROC) analysis

Park JS, Nam HS, Kim YB, Choi YJ, Lee SH, Kim SH

Many allergists are currently focusing on the development of new diagnostic tools, and are attempting to improve both the sensitivity and specificity. A multiple allergen simultaneous test-chemiluminescent assay (MAST-CLA) is...
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Activated Charcoal Suppresses Breeding of the House Dust Mite, Dermatophagoides Pteronyssinus, in Culture

Nam HS, Siebers R, Lee SH, Kim SH, Lee SH, Crane J

House dust mite sensitized asthmatics are advised to practice allergen avoidance. Charcoal pillows are used in Korea with unsubstantiated claims regarding their efficacy in alleviating asthma symptoms. We tested the...
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IL-12 Production in Lipopolysaccharide- and Dermatophagoides pteronyssinus- Copulsed Monocyte-derived Dendritic Cells

  • KMID: 2234385
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Sep;26(3):200-205.
BACKGROUND: Epidemiological studies have provided indirect evidence that exposure to less invasive microbials enhances the development of allergic diseases. Nonetheless, our understanding of the mechanisms that underlie this apparent symbiosis...
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