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Isoniazid resistance and the point mutation of codon 463 of katG gene of Mycobacterium tuberculosis

Shim TS, Yoo CG, Han SK, Shim YS, Kim YW

It has long been known that almost all isoniazid (INH) resistant mycobacteria lose the catalase and peroxidase activities along with reduced or no virulence for guinea pigs. Recently resistance...
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