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I-shaped incisions for papilla reconstruction in second stage implant surgery

Lee EK, Herr Y, Kwon YH, Shin SI, Lee DY, Chung JH

PURPOSE: Pink gingival esthetic especially on the anterior teeth has been an important success criterion in implant-supported restoration. Inter-implant papillae are a critical factor for implant esthetics, and various techniques...
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Expression Patterns of Tbx1 during Development of the Mouse Mandibular First Molar

Bok SM, Chung KC, Cho ES

  • KMID: 2224469
  • Korean J Anat.
  • 2006 Jun;39(3):187-195.
A T-box transcription factor gene, Tbx1 is a principal candidate of the most frequent chromosomal deletion syndrome found in human, DiGeorge/velocardiofacial syndrome which is a complex developmental disorder associated with cardiac outflow...
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Odontogenic myxoma: report of 2 cases

Kim JY, Park GM, Cho BH, Nah KS

  • KMID: 2034004
  • Korean J Oral Maxillofac Radiol.
  • 2002 Dec;32(4):231-234.
The odontogenic myxoma is an infiltrative benign tumor of bone that occurs almost exclusively in the jaw bones and comprises 3% to 6% of odontogenic tumors. This neoplasm is thought...
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The Effects of Irradiation and Calcium-deficient Diet on the Expression of Bone Morphogenetic Protein-2/4 during Early Tooth Development

Park DH, Hwang EH, Lee SR

  • KMID: 1924087
  • Korean J Oral Maxillofac Radiol.
  • 2000 Sep;30(3):169-181.
PURPOSE: To investigate the expression of bone morphogenetic protein(BMP)-2/4 during eary tooth development after irradiation and calcium-deficient diet. MATERIALS AND METHODS: The pregnant three-week-old Sprague-Dawley rats were used for the...
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Evaluation of osteogenic activity and mineralization of cultured human dental papilla-derived cells

Park BW, Byun JH, Choi MJ, Hah YS, Kim DR, Cho YC, Sung IY, Kim JR

  • KMID: 2328009
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2007 Jul;29(4):279-288.
In the present study, we focused on stem cells in the dental papilla of the tooth germ. The tooth germ, sometimes called the tooth bud, is the primordial structure from...
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Effect of Metformin on Cell Growth and Differentiation in Cultured Odontoblasts

Oh CY, Kim SG, Go DS, Yu SK, Kim TH, Kim CS, Park JC, Kim DK

Metformin (1,1-dimethylbiguanide hydrochloride), derived from French lilac (Galega officinalis), is a first-line anti-diabetic drug prescribed for patients with type 2 diabetes. However, the role of metformin in odontoblastic cell differentiation...
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Modulation of osteoblastic/odontoblastic differentiation of adult mesenchymal stem cells through gene introduction: a brief review

Kim JY, Kim MR, Kim SJ

Bone tissue engineering is one of the important therapeutic approaches to the regeneration of bones in the entire field of regeneration medicine. Mesenchymal stem cells (MSCs) are actively discussed as...
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Neurogenic differentiation of human dental stem cells in vitro

Lee JH, Um S, Song IS, Kim HY, Seo BM

OBJECTIVES: The purpose of this study was to investigate the neurogenic differentiation of human dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), and stem cells from apical papilla...
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Apoptosis during Rat Tooth Development

Kim MJ, Kim YS, Moon YH, Jung NR, Moon JS, Kim SH, Kim MS

  • KMID: 2135281
  • Int J Oral Biol.
  • 2011 Mar;36(1):31-35.
Teeth develop via a reciprocal induction between the ectomesenchyme originating from the neural crest and the ectodermal epithelium. During complete formation of the tooth morphology and structure, many cells proliferate,...
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Expression of Uchl1 in the Dental Epithelium during Mouse Tooth Development

Kim HS, Kim DW, Yang JY, Jang EH, Kim TH, Cho ES

  • KMID: 2283414
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):235-244.
Tooth is formed by the reciprocal interactions between the ectoderm and ectomesenchyme derived from neural crest. It has not been clear that neuronal factors involved in the morphogenesis and differentiation...
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Role of OD314 During Odontoblast Differentiation

Park JC, Kim IH, Kim HJ, Jeong MJ, Oh HJ, Jeong JO, Son HH

  • KMID: 2283208
  • Korean J Phys Anthropol.
  • 2005 Sep;18(3):187-196.
Odontoblasts are responsible for the formation and maintenance of dentin which is a mineralized part in dentin-pulp complex of tooth. OD314 was obtained by subtractive hybridization between odontoblasts and osteoblast/dental...
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Thioredoxin Peroxidases are Differentially Expressed in Developing Tooth Germs in Rats

Kim HJ, Kang JH, Jeon SK, Jung SW, Kim MS, Kim WJ, Oh WM, Lee EJ, Jung JY, Bae CS, Kim SH

  • KMID: 2092887
  • Korean J Anat.
  • 2007 Mar;40(1):27-35.
Thioredoxin peroxidase (prdx)is an antioxidant defense enzyme and is involved in cell differentiation.We elucidated the localization and expression of prdx in the rat tooth germ,which undergoes dynamic morphological changes during...
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Odontogenic Myxoma of Maxilla: A Case Roport

Jang JW, Choi SY, Kim JW, Byeon KJ, Kim CS

  • KMID: 1474195
  • J Korean Assoc Oral Maxillofac Surg.
  • 2009 Dec;35(6):486-489.
Odontogenic Myxoma of the jaws is a rare benign tumor derived from embryonic mesenchymal elements of dental anlage. It appears to originate from the dental papilla, follicle or periodontal ligament....
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The effect of peri-implant bone exposure on soft tissue healing and bone loss in two adjacent implants

Shin SY, Kye SB, Hong J, Paeng JY, Yang SM

PURPOSE: The purpose of this study was to evaluate the soft tissue and bone change around two adjacent implants in one-stage implant surgery. METHODS: Eleven subjects (7 males, 4 females) who...
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Fibromyxoma Arising from the Maxilla: A Case Report

Suh SH, Kim SR, Jung YS, Kang HJ

  • KMID: 2274604
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Oct;42(10):3121-3125.
Fibromyxomatous lesions of the maxilla are rare. Although other locations are also uncommon, this tumor can occasionally be found in jawbone. They are slow-growing, which result in expansion of the...
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Effects of Chitosan on the Differentiation of MDPC-23 Cells

Park JH, Kim DK, Park JT, Kim SY, Yu SK, Cho KH, Kim HJ

  • KMID: 1457181
  • Int J Oral Biol.
  • 2010 Sep;35(3):91-97.
The effects of chitosan upon the experimentally induced differentiation of MDPC-23 cells, derived from mouse dental papilla cells, were investigated by RT-PCR, observations of cell morphology and Alizaline red-S staining....
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Bisphosphonate and the Eruption of Developing Teeth: Its Effects and Mechanism

Kim HJ, Chung JY, Kim SH

  • KMID: 1512993
  • Korean J Phys Anthropol.
  • 2006 Mar;19(1):73-83.
Bisphosphonates have similar chemical structures to endogenous inorganic pyrophosphate which inhibits mineral deposition in biological tissues. Even though their clinical applications have been attempted, their molecular mechanism and cellular effects...
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Induced Pluripotent Stem (iPS) Cells in Dentistry: A Review

Malhotra N

iPS cells are derived from somatic cells via transduction and expression of selective transcription factors. Both viral-integrating (like retroviral) and non-integrating (like, mRNA or protein-based) techniques are available for the...
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Nfic regulates tooth root patterning and growth

Kim TH, Bae CH, Yang S, Park JC, Cho ES

Molecular interactions between epithelium and mesenchyme are important for root formation. Nuclear factor I-C (Nfic) has been identified as a key regulator of root formation. However, the mechanisms of root...
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Requirement of Smad4-mediated signaling in odontoblast differentiation and dentin matrix formation

Yun CY, Choi H, You YJ, Yang JY, Baek JA, Cho ES

Dentin is the major part of tooth and formed by odontoblasts. Under the influence of the inner enamel epithelium, odontoblasts differentiate from ectomesenchymal cells of the dental papilla and secrete...
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