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A Voxel Based Morphometric Analysis of Longitudinal Cortical Gray Matter Changes in Progranulin Mutation Carriers At-Risk for Frontotemporal Dementia: Preliminary Study

Youn YC, Hsiung GY

BACKGROUND AND PURPOSE: One of the most common genetic causes of frontotemporal dementia (FTD) is mutation in the progranulin (PGRN) gene. The aim of this study is to assess the...
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The Clinical Characteristics according to the Educational Level in the Elderly Patients with Mild Alzheimer's Disease Dementia

Shin DS, Shin HS, Lee SK, Lee DH, Park JH, Lee TK, Sung KB, Yang KI, Park SA

BACKGROUND AND PURPOSE: Cognitive reserve is important for the individual susceptibility to dementia. Among the various determinants of cognitive reserve, the number of years of formal education would be of...
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Atypical Early-Onset Alzheimer's Disease Dementia Diagnosed by Biomarker Study

Lee SK, Shin DS, Shin HS, Kim JH, Park SA

BACKGROUND: The described clinical characteristics of early-onset Alzheimer's disease (EOAD) are distinct from that of late-onset AD. We reported a patient with atypical EOAD. CASE REPORT: A 54-year-old, truck driver developed...
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report

Pan KH, Kim JH, Kim BJ, Lee CN

BACKGROUND: Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis was discovered less than 10 years ago. Its symptoms and characteristics are not well-defined yet. We experienced a case of anti-NMDA receptor encephalitis with phonemic...
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Constructing a Composite Score for the Seoul Neuropsychological Screening Battery-Core

Jahng S, Na DL, Kang Y

BACKGROUND AND PURPOSE: The brief version of the Seoul Neuropsychological Screening Battery (SNSB), the SNSB-Core (SNSB-C), has been developed. Although each subtest score of the SNSB-C provides information on different...
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Hashimoto's Encephalopathy with Positive 14-3-3 Protein in the Cerebrospinal Fluid and Atypical Course Mimicking Creutzfeldt-Jakob Disease

Yoon JE, Kim JS, Lee KB, Roh H, Ahn MY

BACKGROUND: Creutzfeldt-Jakob disease (CJD) shares common clinical features with Hashimoto's encephalopathy (HE). The 14-3-3 protein is a relatively sensitive and specific marker of CJD but is not commonly detected in...
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Effect of Illiteracy on Cognition and Cerebral Morphology in Later Life

Kwon OD, Yoon U, Na DL

BACKGROUND AND PURPOSE: A better developmental environment has positive effects on brain development. The acquisition of literacy during childhood may affect brain functional organization. The present study aimed to evaluate...
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Reduced Gray Matter Volume in Subjective Cognitive Decline: A Voxel-Based Morphometric Study

Choi Y, Yoon BN, Choi SH, Lim MK, Kim HJ, Yang DW

BACKGROUND AND PURPOSE: Subjective cognitive decline has been proposed as a potential indicator of the preclinical state of Alzheimer's disease (AD). The results of the studies of cortical atrophy on...
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