- Long-acting Injectable Antipsychotics in First-episode Schizophrenia
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Jeong HG, Lee MS
- KMID: 2171189
- Clin Psychopharmacol Neurosci.
- 2013 Apr;11(1):1-6.
Antipsychotic medications are important for the successful management of schizophrenia. Continuous treatment with medication is superior in relapse prevention and non-adherence to antipsychotic medication is associated with a poor clinical... -
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- Extended Blood Drug Concentrations in Extended Release Formulated Acetaminophen Overdose Patients
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Bum JH, Rhee N, Kim MJ, Park JS, Kim HJ, Chung SP, Lee HS
- KMID: 2101638
- J Korean Soc Clin Toxicol.
- 2011 Dec;9(2):71-76.
PURPOSE: The Rumack-Matthew nomogram cannot be applied in managing overdose by extended release (ER) preparation acetaminophen (AAP). This study analyzed the clinical characteristics of ER preparation AAP overdose in order... -
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- Sustained-released mixture of vascular endothelial growth factor 165 and fibrin glue strengthens healing of ileal anastomoses in a rabbit model with intraperitoneal infection
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Li Z, Wang W, Wang X, Jiang L, Wang F, Liu Q
- KMID: 2398963
- Ann Surg Treat Res.
- 2017 Sep;93(3):159-165.
- doi: 10.4174/astr.2017.93.3.159
PURPOSE: To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses. METHODS: One hundred twenty-eight... -
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- Respiratory Depression during Oral MS-Contin Administration for Pain Management of Gall Bladder Cancer
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Lee CW, Lee BH, Lee YH
- KMID: 2104771
- J Korean Pain Soc.
- 1996 Jun;9(1):239-243.
MS-Contin is an oral controlled-release preparation of morphine sulfate that has been used widely in the management of advanced cancer pain. It prolongs plasma concentration of morphine with no observable... -
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- Attitudes of Korean Psychiatrists Toward Treatment Long-acting Injectable Antipsychotic
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Park H, Bae SM, Ryoo JH, Kim SI, Lim WJ
- KMID: 2066558
- J Korean Neuropsychiatr Assoc.
- 2009 May;48(3):182-189.
OBJECTIVES : Long acting injectable antipsychotic medication have the ability to sustain the drug effect for a long duration, thus enabling advances in the management of those psychiatric patients who... -
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- Efficacy and Safety of Aceclofenac Controlled Release in Patients with Knee Osteoarthritis: A 4-week, Multicenter, Randomized, Comparative Clinical Study
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Moon YW, Kang SB, Kim TK, Lee MC
- KMID: 2094275
- Knee Surg Relat Res.
- 2014 Mar;26(1):33-42.
- doi: 10.5792/ksrr.2014.26.1.33
PURPOSE: To evaluate the analgesic effect, efficacy and safety of aceclofenac controlled release (CR) in patients with chronic knee osteoarthritis (OA). MATERIALS AND METHODS: A total of 125 subjects with chronic... -
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- Efficacy and Tolerability of OROS Hydromorphone in Strong Opioid-Naive Patients: An Open Label, Prospective Study
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Hwang JE, Kim DE, Kim HN, Yoon JY, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 2258999
- Korean J Med.
- 2011 Mar;80(3):317-322.
BACKGROUND/AIMS: OROS hydromorphone is a synthetic opioid agent. While clinical studies have tested its effectiveness at controlling cancer-associated pain in patients who have received other strong opioids, no clinical studies... -
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- Pharmacokinetic comparison of two valproic acid formulations: a plain and a controlled release enteric-coated tablets
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Rha JH, Jang IJ, Lee KH, Chong WS, Shin SG, Lee N, Myung HJ
- KMID: 2157507
- J Korean Med Sci.
- 1993 Aug;8(4):251-256.
- doi: 10.3346/jkms.1993.8.4.251
We investigated the single- and multiple dose pharmacokinetics of a new controlled-release formulation (Orfil retard enteric coated tablet) of valproic acid in comparison with those of the plain tablet as... -
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- Pharmacological and Safety Profile of Dexlansoprazole: A New Proton Pump Inhibitor - Implications for Treatment of Gastroesophageal Reflux Disease in the Asia Pacific Region
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Goh KL, Choi MG, Hsu PI, Chun HJ, Mahachai V, Kachintorn U, Leelakusolvong S, Kim N, Rani AA, Wong BC, Wu J, Chiu CT, Shetty V, Bocobo JC, Chan MM, Lin JT
- KMID: 2327943
- J Neurogastroenterol Motil.
- 2016 Jul;22(3):355-366.
- doi: 10.5056/jnm15150
Although gastroesophageal reflux disease is not as common in Asia as in western countries, the prevalence has increased substantially during the past decade. Gastroesophageal reflux disease is associated with considerable... -
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- Fabrication of an alpha-lipoic acid-eluting poly-(D,L-lactide-co-caprolactone) cuff for the inhibition of neointimal formation
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Lee HJ, Choi SH, Nah MH, Lim JO, Lee IK
- KMID: 756283
- Exp Mol Med.
- 2009 Jan;41(1):25-32.
- doi: 10.3858/emm.2009.41.1.004
The purpose of this study was to develop a novel polymer cuff for the local delivery of alpha-lipoic acid (ALA) to inhibit neointimal formation in vivo. The polymer cuff was... -
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- Efficacy and Safety of Sustained-Release Recombinant Human Growth Hormone in Korean Adults with Growth Hormone Deficiency
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Kim Y, Hong JW, Chung YS, Kim SW, Cho YW, Kim JH, Kim BJ, Lee EJ
- KMID: 2130831
- Yonsei Med J.
- 2014 Jul;55(4):1042-1048.
- doi: 10.3349/ymj.2014.55.4.1042
PURPOSE: The administration of recombinant human growth hormone in adults with growth hormone deficiency has been known to improve metabolic impairment and quality of life. Patients, however, have to tolerate... -
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- Pharmacokinetics of intravitreally injected liposome-encapsulated tobramycin in normal rabbits
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Kim EK, Kim HB
- KMID: 1729577
- Yonsei Med J.
- 1990 Dec;31(4):308-314.
- doi: 10.3349/ymj.1990.31.4.308
Bacterial endophthalmitis, which is a devastating complication of intraocular surgery or eye trauma, has a poor prognosis. Intravitreal injection of antimicrobial agents has become a part of the standard treatment... -
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- Modified Release Tacrolimus
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First MR, Fitzsimmons WE
- KMID: 1726178
- Yonsei Med J.
- 2004 Dec;45(6):1127-1131.
- doi: 10.3349/ymj.2004.45.6.1127
Modified Release (MR) tacrolimus is an extended release formulation of tacrolimus (Prograf (R) ) administered once daily in the morning. In healthy volunteers, the MR tacrolimus formulation given qd AM... -
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- Evaluation of the effect of a 3rd GnRH injection administered six days after the 2nd GnRH injection of Ovsynch on the reproductive performance of Japanese black cows
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Gaja AO, Hamana K, Kubota C, Kojima T
- KMID: 1718580
- J Vet Sci.
- 2008 Sep;9(3):273-279.
- doi: 10.4142/jvs.2008.9.3.273
This study was designed to evaluate the reproductive performance of Japanese black cows following the 3rd injection of gonadotropin releasing hormone (GnRH) analogue administered concurrently with Ovsynch-based treatment on day... -
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- Therapeutic evaluation of sustained-releasing praziquantel (SRP) for clonorchiasis: Phase 1 and 2 clinical studies
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Choi MH, Chang BC, Lee SJ, Jang IJ, Shin SG, Kho WG, Chun JH, Hong ST
- KMID: 1088768
- Korean J Parasitol.
- 2006 Dec;44(4):361-366.
- doi: 10.3347/kjp.2006.44.4.361
Sustained-releasing praziquantel (SRP) tablet was designed for single dose treatment regimen of clonorchiasis. A previous pre-clinical study confirmed its sustained-releasing characteristics and a better cure rate than conventional praziquantel (PZQ).... -
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