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A Correlation between Serum Level of Alkaline Phosphatase and Acne Severity in Children and Adolescents: A Retrospective Cross-Sectional Study

Jue MS, Park E, Kang HS, Kim JS

Background: Acne is a chronic inflammatory disease of the pilosebaceous unit and usually affects adolescents when the peak concentrations of growth hormone, insulin-like growth factor 1, and androgen are demonstrated....
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Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain

Choi SR, Beitz AJ, Lee JH

We have previously demonstrated that the neurosteroid dehydroepiandrosterone sulfate (DHEAS) induces functional potentiation of N-methyl-D-aspartate (NMDA) receptors via increases in phosphorylation of NMDA receptor GluN1 subunit (pGluN1). However, the modulatory...
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The association between serum dehydroepiandrosterone sulfate (DHEAS) levels and job-related stress among female nurses

Cho S, Park WJ, Kang W, Lim HM, Ahn JS, Lim DY, Moon JD

BACKGROUND: Dehydroepiandrosterone sulfate (DHEAS) is an endogenous steroid hormone produced by the adrenal gland. DHEAS has been suggested to play a protective role against psychosocial stress. The aim of this...
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Association between Body Mass Index and Serum Dehydroepiandrosterone Sulfate Level in 8-Year-Old Girls

Na JH, Kim YH, Hong SJ, Kim JK

BACKGROUND: Adiposity may play a role as a potential trigger for adrenarche. The purpose of this study was to evaluate the association between body mass index (BMI) and serum dehydroepiandrosterone...
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The association between skeletal maturation and adrenal androgen levels in obese children and adolescents

Kim SE, Jang JW, Ahn MB, Kim SH, Cho WK, Cho KS, Park SH, Jung MH, Suh BK

PURPOSE: This study aimed to investigate the association between skeletal maturation and adrenal androgen levels in obese children and adolescents. METHODS: Fifty-three children and adolescents (aged 7–15 years) diagnosed as obese...
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Dehydroepiandrosterone Sulfate Level Varies Nonlinearly with Symptom Severity in Major Depressive Disorder

Uh D, Jeong HG, Choi KY, Oh SY, Lee S, Kim SH, Joe SH

OBJECTIVE: The pathophysiology of major depressive disorder (MDD) is still not well understood. Conflicting results for surrogate biomarkers in MDD have been reported, which might be a consequence of the...
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The Association between Dehydroepiandrosterone Sulfate (DHEA-S) and Bone Mineral Density in Korean Men and Women

Park SG, Hwang S, Kim JS, Park KC, Kwon Y, Kim KC

BACKGROUND: The relationship between dehydroepiandrosterone sulfate (DHEA-S) and bone mineral density (BMD) is controversial. And findings of most studies that have investigated this relationship are restricted to postmenopausal women. In...
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Limited Diagnostic Utility of Plasma Adrenocorticotropic Hormone for Differentiation between Adrenal Cushing Syndrome and Cushing Disease

Hong AR, Kim JH, Hong ES, Kim IK, Park KS, Ahn CH, Kim SW, Shin CS, Kim SY

BACKGROUND: Measurement of the plasma adrenocorticotropic hormone (ACTH) level has been recommended as the first diagnostic test for differentiating between ACTH-independent Cushing syndrome (CS) and ACTH-dependent CS. When plasma ACTH...
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Dehydroepiandrosterone Sulfate as a Risk Factor for Premature Myocardial Infarction: A Comparative Study

Shojaie M, Rajpout MY, Abtahian A, Pour AE, Ghobadifar MA, Akbarzadeh A

BACKGROUND: This study aimed to evaluate some of the major risk factors of myocardial infarction including dehydroepiandrosterone sulfate in patients with premature myocardial infarction (age or =50 years). METHODS: This...
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Effects of Long-term Administration of the Antiaging Hormone Dehydroepiandrosterone Sulfate on Rat Prostates and Testes as Androgen-Dependent Organs

Sah C, Aridogan I, Izol V, Erdogan S, Doran S

  • KMID: 2430623
  • Korean J Urol.
  • 2013 Mar;54(3):199-203.
PURPOSE: This study aimed to determine the effects of the long-term use of dehydroepiandrosterone sulfate (DHEAS) on rat prostates and testes as well as on serum testosterone and DHEAS levels. MATERIALS...
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The Effects of Galantamine Hydrobromide Treatment on Dehydroepiandrosterone Sulfate and Cortisol Levels in Patients with Chronic Fatigue Syndrome

Turan T, Izgi HB, Ozsoy S, Tanriverdi F, Basturk M, Asdemir A, Besirli A, Esel E, Sofuoglu S

  • KMID: 2315838
  • Psychiatry Investig.
  • 2009 Sep;6(3):204-210.
OBJECTIVE: Mental fatigue, cognitive disorders, and sleep disturbances seen in chronic fatigue syndrome (CFS) may be attributed to cholinergic deficit. A functional deficiency of cholinergic neurotransmission may cause the hypothalamic-pituitary-adrenal...
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Declining concentrations of dehydroepiandrosterone sulfate and free testosterone with advancing age

Han MS, Choi IJ

  • KMID: 1474966
  • Korean J Obstet Gynecol.
  • 2009 Jun;52(6):631-635.
OBJECTIVE: To investigate the relationship between serum dehydroepiandrosterone sulfate (DHEAS) or free testosterone (FT) levels and aging. METHODS:One hundred and thirty one women without androgen excess symptoms such as oligomenorrhea or...
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Sleep-Related Erections(SREs) in Chronic Vegetative State Patients

Seo CD, Ko KT, Park SY, Lee SW, Lee WK, Kim SY, Kim H, Yang DY

  • KMID: 2299442
  • Korean J Androl.
  • 2006 Apr;24(1):23-28.
PURPOSE: To determine whether sleep-related erections(SREs) occur during chronic vegetative state and if so, to investigate what factors are involved. MATERIALS AND METHODS: Twenty-six men in a vegetative state aged 16~65...
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Effect of Dehydroepiandrosterone Sulfate on Cardiovascular Risk Factors

Kim YJ, Park NC, Kim YJ, Lee SY, Choi SH, Min HG

  • KMID: 2227031
  • Korean J Androl.
  • 2003 Dec;21(3):158-163.
PURPOSE: Morbidity and mortality from cardiovascular disease have increased in Korea. Some studies have suggested that dehydroepiandrosterone sulfate(DHEAS) may play an important role in the pathogenesis or prevention of cardiovascular...
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Clinical Features and Serum Dehydroepiandrosterone Sulfate and Total Testosterone Levels in Female Patients with Androgenetic Alopecia

Lee HJ, Ryu HS, Kim DW, Lee SJ, Chung SL

  • KMID: 2303184
  • Korean J Dermatol.
  • 2001 Jan;39(1):58-67.
BACKGROUND: The development of androgenetic alopecia is thought to be caused by increased androgen action on the hair follicles in the genetically predisposed person. Although most reports about dehydroepiandrosterone sulfate(DHEA-S)...
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Plasma Levels of Dehydroepiandrosterone Sulfate ( DHEA - S ) and Total Testosterone in the Patients with Female androgenetic Alopecia

Yun SK, Kim HY, Ihm CW

  • KMID: 2230759
  • Korean J Dermatol.
  • 1995 Dec;33(6):1060-1065.
BACKGROUND: It has been known that androgenetic alopecia in both male and female is due to the role of the androgen hormone in the hair follicle, but the level of...
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Insulin Resistance, Body Fat Distribution, and Sex Hormones in Healthy Men and Premenopausal Women

Kim SY, Park KS, Cho BY, Lee HK, Shin CS, Koh CS, Oh TG, Kim WB

  • KMID: 2461532
  • J Korean Soc Endocrinol.
  • 1994 Dec;9(4):366-374.
It is well known that obesity central obesity is associated with insulin resistance and some studies reported that sex hormones were associated with insulin resistance. Recently, low levels of sex-hormone...
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