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Five-Repetition Sit-to-Stand Test Performance in Healthy Individuals: Reference Values and Predictors From 2 Prospective Cohorts

Klukowska AM, Staartjes VE, Vandertop WP, Schröder ML

Objective: The 5-repetition-sit-to-stand (5R-STS) test is an objective test of functional impairment- commonly used in various diseases, including lumbar degenerative disc diseases. It is used to measure the severity of...
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Current Concepts of Degenerative Disc Disease -A Significance of Endplate-

Soh J, Jang HD, Shin BJ

Degenerative disc disease has traditionally been thought of as low back pain caused by changes in the nucleus pulposus and annulus fibrous, in recent studies, however, changes in the upper...
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Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma

Rajasekaran S, Tangavel C, Soundararajan DCR, Nayagam SM, Matchado MS, Muthurajan R, Anand KSV, Rajendran S, Shetty AP, Kanna RM, Kuppamuthu D

Objective: To catalog and characterize the proteome of normal human intervertebral disc (IVD). Methods: Nine magnetic resonance imaging (MRI) normal IVDs were harvested from 9 different brain dead yet alive voluntary...
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Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures

Stienen MN, Maldaner N, Sosnova M, Joswig H, Corniola M, Regli L, Hildebrandt G, Schaller K, Gautschi O

Objective: The patient-reported outcome measure (PROM)-based evaluation in lumbar degenerative disc disease (DDD) is today’s gold standard but has limitations. We studied the impact of lower extremity motor deficits (LEMDs)...
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Comparison of Adjacent Segment Degeneration, Cervical Alignment, and Clinical Outcomes after One- and Multilevel Anterior Cervical Discectomy and Fusion

Shin JJ

OBJECTIVE: This study aimed to assess the influence of a fused segment on cervical range of motion (ROM) and adjacent segmental kinematics and determine whether increasing number of fusion levels...
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Cauda Equina Syndrome by Facet Synovial Pseudocyst Secondary to Epidural Injection

Kang MS, Lee YR, Kim TH, Lee SH

A 77-year-old woman presented with bilateral leg weakness, accompanied by severe axial back and radicular pain, after a L4–5 epidural injection. She had been receiving misappropriated epidural injections for the...
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Nucleoplasty: Percutaneous Plasma Disc Decompression for the Treatment of Lumbar Disc Herniation

Lee DY, Jeong ST, Oh JY, Kim DH

STUDY DESIGN: A review of the literature regarding nucleoplasty. OBJECTIVES: This aim of this article is to provide current information on nucleoplasty as a therapeutic intervention for herniated disc or discogenic...
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The Clinical Correlations between Diabetes, Cigarette Smoking and Obesity on Intervertebral Degenerative Disc Disease of the Lumbar Spine

Jakoi AM, Pannu G, D'Oro A, Buser Z, Pham MH, Patel NN, Hsieh PC, Liu JC, Acosta FL, Hah R, Wang JC

STUDY DESIGN: Retrospective analysis of a nationwide private insurance database. Chi-square analysis and linear regression models were utilized for outcome measures. PURPOSE: The purpose of this study was to investigate any...
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Reliable Magnetic Resonance Imaging Based Grading System for Cervical Intervertebral Disc Degeneration

Jacobs LJ, Chen AF, Kang JD, Lee JY

STUDY DESIGN: Observational. PURPOSE: To develop a simple and comprehensive grading system for cervical discs that precisely, consistently and meaningfully presents radiologic and morphologic data. OVERVIEW OF LITERATURE: The Thompson grading system...
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Total Disc Replacement in Lumbar Degenerative Disc Diseases

Park CK

More than 10 years have passed since lumbar total disc replacement (LTDR) was introduced for the first time to the world market for the surgical management of lumbar degenerative disc...
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Comparative Analysis of Cervical Disc Arthroplasty Using Two Types of Artificial Cervical Discs: Bryan(R) versus Mobi-C(R)

Choi DH, Kim WK, Lee SG, Park CW

OBJECTIVE: Since the 1990s, due to postoperative loss of mobility and adjacent segmental disease after anterior cervical fusion, many different types of cervical artificial discs have been developed as alternative...
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Long Term Efficacy of Posterior Lumbar Interbody Fusion with Standard Cages alone in Lumbar Disc Diseases Combined with Modic Changes

Kwon YM, Chin DK, Jin BH, Kim KS, Cho YE, Kuh SU

OBJECTIVE: Posterior lumbar interbody fusion (PLIF) is considered to have the best theoretical potential in promoting bony fusion of unstable vertebral segments by way of a load sharing effect of...
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Clinical and Radiographic Analysis of Cervical Total Disc Replacement Versus Anterior Cervical fusion using Stand-alone Cage

Kim BJ, Tae HS, Cho TH, Suh JK

  • KMID: 2288412
  • Korean J Spine.
  • 2009 Mar;6(1):11-16.
OBJECTIVE: Total intervertebral disc replacement is designed to preserve motion and avoid limitations of fusion after removing local pathology. The authors report the results of a signle-center study to determine...
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Surgical Treatment of Degenerative Lumbar Disc Disease

Cho KH

Low back pain is an extremely common symptom. Approximately 80% of the general population experience a memorable episode of back pain in their lives. The patients suffering from chronic low...
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A Retrospective Study of the Fusion Rate and Clinical Outcome after Mini-open ALIF using Paired Stand-alone Rectangular Cages

Choi JY, Jeong HT, Hyun YI, Sung YS, Lee WS, Sung KH

  • KMID: 1905013
  • J Korean Neurosurg Soc.
  • 2004 Jul;36(1):28-33.
OBJECTIVE: We conduct a study to determine the fusion rate and clinical outcome after mini-open anterior lumbar interbody fusion(ALIF) in selected patients with a degenerative lumbar disc disease. METHODS: Ninety-four...
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Effect of PDN(R)(Prosthetic Disc Nucleus) on the Mobility and Height of the Intervertebral Disc: Preliminary Report

Lee SH, Kim DY, Shim CS, Choi WC, Choi G, Lee HY

  • KMID: 2018724
  • J Korean Neurosurg Soc.
  • 2004 May;35(5):483-486.
OBJECTIVE: The purpose of the current study is to investigate the effect of the prosthetic disc nucleus replacement on the mobility and height of the intervertebral disc and adjacent segments....
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Midterm Follow-up Results of Anterior Cervical Microforaminotomy

Kim YG, Lee JS, Park MS, Ha HG

  • KMID: 2339790
  • J Korean Neurosurg Soc.
  • 2004 Mar;35(3):250-255.
OBJECTIVE: We have previously reported excellent early clinical results of anterior cervical microforaminotomy(ACMF) for patients who have cervical radiculopathy from either disc herniation or foraminal stenosis. ACMF is being accepted...
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The Distributions and Changes of Nerve Fiber in Human Nucleus Pulposus According to the Degenerative Changes

Yang JY, Lee JK, Choi US, Lee HH, Woo SM, Lee JB

STUDY DESIGN: This was a retrospective study to evaluate the nerve fibers in human nucleus pulposus. OBJECTIVE: To study the changes in the pain receptor, including the nerve fiber of the...
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Anterior Lumbar Interbody Fusion for Focal Type of Degenerative Flat Back: Preliminary Report

Shim CS, Lee SH, Lim SR, Jung BJ, Choi WC, Chung SK

  • KMID: 2188874
  • J Korean Neurosurg Soc.
  • 2003 May;33(5):460-465.
OBJECTIVE: The purpose of this study is to determine the efficacy of anterior lumbar interbody fusion(ALIF) for the patients with focal type of degenerative flat back. METHODS: The authors reviewed...
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The Efficacy of Anterior Lumbar Interbody Fusion in Degenerative Disc Disease and Degenerative Spondylolisthesis: Comparative Review of 44 Single-Level Cases

Chung SK, Ha SI, Lee SH, Lim SR, Lee HY

  • KMID: 1904657
  • J Korean Neurosurg Soc.
  • 2002 May;31(5):429-434.
OBJECTIVE: The authors conduct a retrospective study to evaluate the efficacy of anterior lumbar interbody fusion(ALIF) in treating degenerative disc disease(DDD) and degenerative spondylolisthesis(DS). METHODS: During 1998, eighty-six patients underwent mini-retroperitoneal...
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