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Effects of decorin, TGF-beta antagonist on wound healing of rats

Yoo WM, Park C, Rah DK, Park BY

  • KMID: 1941848
  • J Korean Soc Plast Reconstr Surg.
  • 1998 Feb;25(2):191-198.
It is known that TGF-beta induces scar in fetal wound healing. The fact gives us that inhibition of TGF-beta can reduce scar formation. It has been reported that neutralizing antibody...
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Effect of decorin on tensile strength of healing flexor tendon

Jeong JW, Ki HS

  • KMID: 2322523
  • J Korean Soc Plast Reconstr Surg.
  • 2000 Jan;27(1):83-86.
Adhesion formed between tendon and its sheath after repair often impairs functional recovery. There have been many attempts to reduce adhesion around a repaired tendon, but most results have been...
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Decorin and TGF-beta Expression after Partial Myotomy of the Extraocular Muscle in Rat

Lim YJ, Kim GN, Lee NE, Kim SJ, Yoo JM

PURPOSE: To report the expression of decorin and TGF-beta in partial myotomy of the extraocular muscle in rats. METHODS: Partial myotomy of the superior rectus muscle was performed on the right...
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Analysis of Proteoglycan Gene Messages in Human Nasal Mucosa and Nasal Polyp using Dot Blot Hybridization

Park JH, Baek SK, Yoo CK, Kim JJ, Cho SD, Lee HM, Lee SH

  • KMID: 2275670
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):606-610.
BACKGROUND AND OBJECTIVES: It has been suggested that the formation and growth of nasal polyp require the remodeling of extracellular matrix. Proteoglycans (PGs) are the major components of the...
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The effect of Decorin, TGF-beta antagonist, on wound healing in rabbits

Song SH, You JY, Kim SH, Kim MS, Yang BE

  • KMID: 2328352
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Aug;27(4):301-307.
There have been many trials to decrease the scar formation followed by wound treatment. TGF-beta plays a important role on wound healing in adult. Therefore the repression of TGF-beta expression...
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Analysis of Gene Expression in Renal Cell Carcinomas Using cDNA Microarray: Reduced Expression of Decorin in Renal Cell Carcinomas

Lee JS, Suh KS, Choi KU, Kim JY, Park DY

  • KMID: 2011749
  • Korean J Pathol.
  • 2003 Aug;37(4):232-238.
BACKGROUND: Identification of the genes expressed differentially in renal cell carcinoma (RCC)but not in the non-cancerous kidney is important for understanding the molecular basis ofrenal cell carcinoma and for defining...
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A Novel Decorin Gene Mutation in Congenital Hereditary Stromal Dystrophy: A Korean Family

Lee JH, Ki CS, Chung ES, Chung TY

A 43-year-old man developed decreased vision in the right eye that had persisted for seven years. Under slit lamp examination, corneal clouding was noted with normal endothelium and ocular structure....
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Effects of Interleukin-6 on mRNA Expression of Alkaline Phosphatase, Osteopontin, Decorin and a1(1)-collagen in Human Bone Marrow Stromal Cells

Kim CH, Kim DK, Park SI, Sohn KH, Kim GS

  • KMID: 2461617
  • J Korean Soc Endocrinol.
  • 1996 Jun;11(2):156-162.
Background: Inter1eukin-6(IL-6) is known to be produced by osteoblastic cells and to have impartant role in regulation of bone remodelling, Most previous studies indicated that IL-6 bas a major role...
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The effect of decorinas an antagonist of tgf-betain fetal rat wound healing

Shin KS, Yoo WM, Kwark HJ

  • KMID: 2119490
  • J Korean Soc Plast Reconstr Surg.
  • 1998 Dec;25(8):1393-1403.
Adult wounds heal with scar-tissue formation, whereas fetal wounds heal without scarring and with a lesser inflammatory and cytokine response. The unique fetal wound repair process is not dependent on...
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Comparative Analysis of Platelet-rich Plasma Effect on Tenocytes from Normal Human Rotator Cuff Tendon and Human Rotator Cuff Tendon with Degenerative Tears

Yoon JY, Lee SY, Shin S, Yoon KS, Jo CH

BACKGROUND: Platelet-rich plasma (PRP) stimulates cell proliferation and enhances matrix gene expression and synthesis. However, there have been no comparative study of the PRP effect on the normal and degenerative...
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NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts

Thu VT, Kim HK, Long LT, Thuy TT, Huy NQ, Kim SH, Kim N, Ko KS, Rhee BD, Han J

Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart...
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The Amniotic Fluid Proteome Differs Significantly between Donor and Recipient Fetuses in Pregnancies Complicated by Twin-to-Twin Transfusion Syndrome

Kim SM, Cho BK, Kim BJ, Lee HY, Norwitz ER, Kang MJ, Lee SM, Park CW, Jun JK, Yi EC, Park JS

BACKGROUND: Twin-to-twin transfusion syndrome (TTTS) is a serious complication of monochorionic twin pregnancies. It results from disproportionate blood supply to each fetus caused by abnormal vascular anastomosis within the placenta....
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