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Antihypertensive Effect of Debrisoquin Sulfate in the Treatment of Hypertension

Song HS, Lee JI, Park HM, Lee CH, Suh SK

Authors observed the antihypertensive effect of debrisoquin sulfate in 35 cases of essential hypertension and following results were obtained. 1) Results of short term control of blood pressure with debrisquin...
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Influence of Phenilamine on Pressor Responses of Norepinephrine and Tyramine

Kim WS, Jung JW, Jang KS, Hong SP, Cho KK, Choi CH, Lim DY

The effect of Pheniramine(Avil), a histaminergic-1 receptor blocking agent presently employed in treating various allergic diseases on pressor actions of norepinephring(NE) and tyramine (TR) was studied in the rabbit. Pheniramine,...
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A Study on the Debrisoquine Metabolism in a Group, of Korean Population

Lee MH, Moon HY, Son MH, Sohn SJ, Choi JS

  • KMID: 2282704
  • Korean J Prev Med.
  • 1994 Sep;27(3):569-580.
The genetically determined ability to metabolize debrisoquine(DBR) is related to risk of lung cancer and DBR hydroxylation exhibits wide inter-individual variation. In this study, 100 korean adults were tested for...
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Monoamine oxidase B gene and Cytochrome P450 2D6 gene polymorphism in sporadic Korean Parkinson's disease

Lee YH, Lim JG, Yi SD, Lee YJ

  • KMID: 2342751
  • J Korean Neurol Assoc.
  • 1999 Jan;17(1):63-71.
BACKGROUND: Epidemiological studies have identified that positive family history and frequent exposures to environmental toxins such as 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) are of prime causative factors for PD. These toxins are...
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