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A radioimmunoassay method for detection of DNA based on chemical immobilization of anti-DNA antibody

Yoo SK, Yoon MO, Park UJ, Han HS, Kim JH, Hwang HJ

  • KMID: 755039
  • Exp Mol Med.
  • 1999 Sep;31(3):122-125.
High selectivity provided by biomolecules such as antibodies and enzymes has been exploited during the last two decades for development of biosensors. Of particular importance are efficient immobilization methods for biomolecules in order...
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Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation

Kim BY, Kim H, Cho EJ, Youn HD

In this study, we investigated the role of Nur77, an orphan nuclear receptor, in HIF-alpha transcriptional activity. We found that Nur77 associates and stabilizes HIF-1alpha via indirect interaction. Nur77 was...
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Human SNF2L Gene Is Regulated Constitutively and Inducibly in Neural Cells via a cAMP-Response Element

Xia Y, Wang L, Ma C, Gong Y, Zhao Y

PURPOSE: SNF2L belongs to Imitation Switch family and plays an essential role in neural tissues and gonads. In our previous studies, we have demonstrated that the basal transcription of human...
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Identification and functional characterization of an alternative splice variant within the fourth exon of human nanog

Kim JS, Kim J, Kim BS, Chung HY, Lee YY, Park CS, Lee YS, Lee YH, Chung IY

  • KMID: 1116205
  • Exp Mol Med.
  • 2005 Dec;37(6):601-607.
Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Here, we report the identification of an alternatively-spliced variant of nanog....
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