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Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells

He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J

  • KMID: 1402316
  • Exp Mol Med.
  • 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors....
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Microsatellite Instability Status of Interval Colorectal Cancers in a Korean Population

Lee KW, Park SK, Yang HJ, Jung YS, Choi KY, Kim KE, Jung KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: A subset of patients may develop colorectal cancer after a colonoscopy that is negative for malignancy. These missed or de novo lesions are referred to as interval cancers. The...
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