- B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
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Choi YW, Kim HJ, Kim YH, Park SH, Chwae YJ, Lee J, Soh EY, Kim JH, Park TJ
- KMID: 2155385
- Exp Mol Med.
- 2014 Nov;46(11):e120.
- doi: 10.1038/emm.2014.68
B-RafV600E mutant is found in 40-70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma... -
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- DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
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Zhou D, Wan Y, Xie D, Wang Y, Wei J, Yan Q, Lu P, Mo L, Xie J, Yang S, Qi X
- KMID: 2155436
- Exp Mol Med.
- 2015 Sep;47(9):e182.
- doi: 10.1038/emm.2015.57
Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on... -
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- Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos
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Cho J, Kang S, Lee BC
- KMID: 1784643
- J Vet Sci.
- 2014 Jun;15(2):225-231.
- doi: 10.4142/jvs.2014.15.2.225
This study was conducted to investigate the expression of three genes related to early embryonic development in bovine transgenic cloned embryos. To accomplish this, development of bovine transgenic somatic cell... -
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