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Enhanced Expressions and Histological Characteristics of Intravenously Administered Plasmid DNA in Rat Lung

Rha SJ, Wang YP

Cationic liposome-mediated gene transfection is a promising method for gene therapy. In this study, the transfection efficiency and histological patterns were evaluated in rat lung after intravenous administration via femoral...
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Optimal salt concentration of vehicle for plasmid DNA enhances gene transfer mediated by electroporation

Lee MJ, Cho SS, Jang HS, Lim YS, You JR, Park JW, Suh HR, Kim JA, Park JS, Kim DK

  • KMID: 931876
  • Exp Mol Med.
  • 2002 Sep;34(4):265-272.
In vivo electroporation has emerged as a leading technology for developing nonviral gene therapies, and the various technical parameters governing electroporation efficiency have been optimized by both theoretical and...
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