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Base excision repair synthesis of DNA containing 8-oxoguanine in Escherichia coli

Lee YS, Chung MH

  • KMID: 1097258
  • Exp Mol Med.
  • 2003 Apr;35(2):106-112.
8-oxo-7,8-dihydroguanine (8-oxo-G) in DNA is a mutagenic adduct formed by reactive oxygen species. In Escherichia coli, 2,6-dihydroxy-5N-formamidopyrimidine (Fapy)-DNA glycosylase (Fpg) removes this mutagenic adduct from DNA. In this report, we...
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