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Tropomyosin-related kinase A (TrkA) plays an important role in cell survival, differentiation, and apoptosis in various neuronal and nonneuronal cell types. Here we show that TrkA overexpression by the Tet-On...
Endothelins (ETs), which were originally found to be potent vasoactive transmitters, were known to be implicated in nervous system, but the mode of mechanism remains unclear. ETs (ET-1, ET-2, and...
Park CE, Ko SM, Kim JM, Yoon MY, Kim JY, Kang IS, Kim SS, Ha JH
KMID: 754991
Exp Mol Med.
1998 Jun;30(2):73-79.
Mammalian acetyl-CoA carboxylase (ACC) is present in two isoforms, alpha and
beta, both of which catalyze formation of malonyl-CoA by fixing CO2 into
acetyl-CoA. ACC-alpha is highly expressed in lipogenic tissues whereas...
Reactive oxygen species (ROS) has been implicated as an inducer of NF-kappaB activity in numbers of cell types where exposure of cells to ROS such as H2O2 leads to NF-kappaB...