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Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines

Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE

PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs...
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B cells activated in the presence of Th1 cytokines inhibit osteoclastogenesis

Choi Y, Kim JJ

  • KMID: 1093611
  • Exp Mol Med.
  • 2003 Oct;35(5):385-392.
Host immune response has been considered as an important disease-modifying factor of periodontitis, however, which immune cell(s) or factor(s) are involved in the destruction of periodontium remains unclear. Previously, we...
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Effect of cytokines on the expression of cell adhesion molecule and on the adhesion of melanoma cells to endothelial cells

Kim SJ, Kim NS, Lee JL

We examined the role of cell adhesion molecules (CAM) by which tumor cells bind to the endothelial cells using human umbilical vein endothelial cells (HUVEC) and cultured melanoma cells. Endothelial...
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Differential Expression, Shedding, Cytokine Regulation and Function of TNFR1 and TNFR2 in Human Fetal Astrocytes

Choi SJ, Lee KH, Park HS, Kim SK, Koh CM, Park JY

  • KMID: 2428299
  • Yonsei Med J.
  • 2005 Dec;46(6):818-826.
Tumor necrosis factor (TNF) -alpha induces pleiotropic cellular effects through a 55kDa, type 1 receptor (TNFR1) and a 75kDa type 2 receptor (TNFR2). Moreover, it participates in the pathogenesis of...
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