- Association between genetic polymorphisms of the cytochromes P-450 (1A1, 2D6, and 2E1) and the susceptibility to pancreatic cancer
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Lee HC, Yoon YB, Kim CY
- KMID: 1051581
- Korean J Intern Med.
- 1997 Jun;12(2):128-136.
OBJECTIVES: Metabolic activation is a prerequisite for the carcinogenic effect of many carcinogens, and considerable interindividual variation exists in the metabolic capacity to activate the carcinogens. The cytochromes P-450 (CYPs)... -
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- Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
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Kim A, Parry EM, Parry JM
- KMID: 1093602
- Exp Mol Med.
- 2002 Mar;34(1):83-89.
Chlorinated organic chemicals are widely used in industry and are present in the environment. Five chlorinated aliphatic hydrocarbons, namely 1-2-dichloroethane, 1,1,2-trichloroethane, trichloroethylene, 2,3-dichlorobutane and 1-chlorohexane were investigated to determine their... -
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- Genetic Polymorphisms of Alcohol-metabolizing Enzymes and Cytokines in Patients with Alcohol Induced Pancreatitis and Alcoholic Liver Cirrhosis
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Kim MS, Lee DH, Kang HS, Park HS, Jung S, Lee JW, Kwon KS, Kim PS, Kim HG, Shin YW, Kim YS, Baek I, Lee MS
- KMID: 772650
- Korean J Gastroenterol.
- 2004 Jun;43(6):355-363.
BACKGROUND/AIMS: Susceptibility to organ damage induced by alcohol may be related to inherited variations (polymorphisms) in alcohol-metabolizing enzymes, or polymorphisms affecting cytokines. The aim of this study was to... -
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