- Association between genetic polymorphisms of the cytochromes P-450 (1A1, 2D6, and 2E1) and the susceptibility to pancreatic cancer
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Lee HC, Yoon YB, Kim CY
- KMID: 1051581
- Korean J Intern Med.
- 1997 Jun;12(2):128-136.
OBJECTIVES: Metabolic activation is a prerequisite for the carcinogenic effect of many carcinogens, and considerable interindividual variation exists in the metabolic capacity to activate the carcinogens. The cytochromes P-450 (CYPs)... -
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- Polymorphism of the CYP1A1 and glutathione-S-transferase gene in Korean lung cancer patients
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Hong YS, Chang JH, Kwon OJ, Ham YA, Choi JH
- KMID: 755008
- Exp Mol Med.
- 1998 Dec;30(4):192-198.
The levels of expressions and catalytic activities of cytochrome P450 (CYP1A1) and glutathione-S-transferase class mu (GSTM1) enzymes in lungs and their metabolic balance may be an important determinant host factor underlying lung cancer.... -
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